Clinical and Biological Characteristics of Hidradenitis Suppurativa

NCT03967600 | Recruiting

• 1 other identifier: 16-19770
• Study Type: observational
• Target: 1,000
• Locations: 1 country
• Sites: 1

Brief Summary

Hidradenitis suppurativa (HS) is a common and debilitating skin disease that is poorly understood and understudied. As a result, little is known about disease prognosis and few effective treatments exist for this condition. This prospective observational cohort study aims to comprehensively characterize the clinical and biological features of HS. The results of this research will provide a basis for the development of an HS clinical classification system and identification of potential treatments for HS.

Conditions

Hidradenitis Suppurativa

Outcome Measures

Primary Outcomes (1)

• The primary aim of this study is to identify clinical and biologic characteristics of hidradenitis suppurativa.

  2016-2026

Secondary Outcomes (1)

• Secondary aims include correlating alterations in clinical and biological characteristics with disease status, and identifying genetic variants that predict disease progression or response to therapy.

  2016-2026

Study Arms (2)

Hidradenitis Suppurativa Patients

Patients with physician diagnosed Hidradenitis Suppurativa

Healthy Volunteers

Healthy volunteers without any skin conditions or recent history of antibiotic use.

Eligibility Criteria

• Age: 13 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with Hidradenitis Suppurativa

You may qualify if:

• Age 13 years or older
• Diagnosis of HS clinically-confirmed by a physician

You may not qualify if:

• \. Inability to give informed consent or have a parent/guardian who is able and willing to give informed consent.
• Healthy Volunteer
• No history of chronic skin conditions
• No recent history of antibiotic use
• \. Inability to give informed consent or have a parent/guardian who is able and willing to give informed consent.

Sponsors & Collaborators

• University of California, San Francisco: lead

Study Sites (1)

University of California, San Francisco

San Francisco, California, 94115, United States

RECRUITING

MeSH Terms

Conditions

Hidradenitis Suppurativa

Condition Hierarchy (Ancestors)

Skin Diseases, Bacterial; Bacterial Infections; Bacterial Infections and Mycoses; Infections; Skin Diseases, Infectious; Suppuration; Skin Diseases; Skin and Connective Tissue Diseases; Hidradenitis; Sweat Gland Diseases

Study Officials

• Haley B Naik, MD, MHSc, FAAD

  University of California, San Francisco

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Kaelin Chatterley

CONTACT

415-961-3786; Kaelin.Chatterley@ucsf.edu

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 10 Years
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 27, 2019
• First Posted: May 30, 2019
• Study Start: July 15, 2016
• Primary Completion (Estimated): July 15, 2026
• Study Completion (Estimated): July 15, 2026
• Last Updated: May 4, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)