Efficacy of Oil Pulling Therapy on Supragingival Plaque Growth

NCT03962777 | Completed

• 1 other identifier: BaskentU5
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

Oil pulling is a method based on Ayurvedic medicine which aims to obtain local and systemic benefits by swirling oils in the oral cavity for a period of 15 minutes, before spitting it out.12 Although the exact mechanism of action is not clear, there are some proposed theories. One proposed theory is the saponification or "soap making" process which occurs as a result of alkali hydrolysis of fat.9 Second theory speculates the inhibition of plaque formation and adhesion of bacteria due to the viscous nature of the oil. 13 According to the third theory, presence of antioxidants in oil prevent lipid peroxidation and thus help to the destruction of microorganisms and potentiating the action of Vitamin E in the oral cavity.14 The effect of oil pulling on halitosis and the use of oil pulling in addition to conventional oral hygiene practices was investigated in some studies13,15,16 but to the best knowledge of the authors, no study has evaluated the plaque-inhibiting effects of oil pulling. Therefore this study was conducted to evaluate the plaque-inhibiting effects of oil pulling using 4- day plaque regrowth study model17,18 compared to 0.2% CHX-containing mouthrinse. The tested hypothesis was that oil pulling would perform plaque regrowth inhibition as well as the CHX-containing mouthrinse.

Conditions

Gingivitis

Keywords

gingivitis; oil pulling

Outcome Measures

Primary Outcomes (1)

• plaque index

  plaque regrowth inhibition will be tested using the Turesky et al. 21 modification of the Quigley and Hein index.a score of 0 to 5 is assigned to each facial and lingual nonrestored surface of all the teeth except third molars, as follows: 0: No plaque; 1:Separate flecks of plaque at the cervical margin of the tooth; 2:A thin continuos band of plaque (up to one mm) at the cervical margin of the tooth; 3: A band of plaque wider than one mm but covering less than one-third of the crown of the tooth; 4:Plaque covering at least one-third but less than two-thirds of the crown of the tooth; 5: Plaque covering two-thirds or more of the crown of the tooth. An index for the entire mouth is determined by dividing the total score by the number surfaces ( a maximum of 2 x 2 x 14 = 56 surfaces) examined.lower values means that the agent has better plaque inhbiting effect

  day 4

Study Arms (2)

oil pulling

EXPERIMENTAL

patients used oil pulling therapy for 4 days

Other: oil pulling

chlorhexidine

ACTIVE COMPARATOR

patients used chlorhexidine digluconate for 4 days

Other: chlorhexidine

Interventions

chlorhexidine OTHER

patients used chx moutrinses for four days

chlorhexidine

oil pulling OTHER

patients used oil pulling for four days

oil pulling

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• no systemic disease
• having ≥ 22 natural teeth,
• having no removable or fixed prostheses or fixed and removable orthodontic appliances.

You may not qualify if:

• use of antibiotics and anti-inflammatory drugs in previous 6 months;
• allergy to any ingredient used in the study;
• smokers;
• pregnant of lactating females;
• history of mouthrinses, gels or chewing gums use that contains antimicrobial agents in the preceding 3 months
• having teeth with probing depth ≥4mm and signs of gingival inflammation.

Sponsors & Collaborators

• Baskent University: lead

Study Sites (1)

Yasemin Sezgin

Ankara, Please Select..., 06690, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Gingivitis

Interventions

Chlorhexidine

Condition Hierarchy (Ancestors)

Infections; Gingival Diseases; Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Biguanides; Guanidines; Amidines; Organic Chemicals

Study Officials

• yasemin sezgin, asst prof

  başkent university, faculty of dentistry

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: asistant professor

Study Record Dates

• First Submitted: May 22, 2019
• First Posted: May 24, 2019
• Study Start: February 9, 2019
• Primary Completion: May 9, 2019
• Study Completion: May 15, 2019
• Last Updated: May 29, 2019

Record last verified: 2019-05

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)