NCT03954912

Brief Summary

This prospective cohort study was conducted with the aim of comparing relevant clinical outcomes which included intra (surgical time and blood loss), post-operative outcomes (range of motion, function, complications and revisions) and return to activity between imageless and image-based surgical system in medial unicondylar knee arthroplasty

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
33

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jun 2015

Typical duration for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2015

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2018

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

May 13, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 17, 2019

Completed
Last Updated

June 20, 2019

Status Verified

June 1, 2019

Enrollment Period

2.6 years

First QC Date

May 13, 2019

Last Update Submit

June 18, 2019

Conditions

Keywords

MAKONAVIOrobotic surgeryUKAsurgical timeKSSKFS

Outcome Measures

Primary Outcomes (2)

  • operative time

    operative time in minutes the higher value of blood loss is worse outcome

    1 day

  • calculated total blood loss

    total blood loss which was calculated using a formula based on patient blood volume and a decrease in hemoglobin

    1 day

Secondary Outcomes (1)

  • post operative complications

    12 months

Study Arms (2)

MAKO robotic assisted UKA

ACTIVE COMPARATOR

image base (MAKO) robotic assisted UKA

Procedure: MAKO assisted unicondylar knee arthroplasty

NAVIO robotic assisted UKA

ACTIVE COMPARATOR

imageless (NAVIO) robotic assisted UKA

Procedure: NAVIO assisted unicondylar knee arthroplasty

Interventions

MAKO assisted

MAKO robotic assisted UKA

NAVIO assisted

NAVIO robotic assisted UKA

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • patients were those deemed suitable for unicondylar knee arthroplasty surgery
  • patients who could give informed consent
  • patients who willing to attend the prescribed follow-up.

You may not qualify if:

  • Patients who have medial osteoarthritis knee with following condition:
  • Ligament insufficiency (anterior cruciate ligament rupture, collateral ligament insufficiency).
  • Inflammatory arthritis
  • A deformity requiring augmentation
  • Neurological movement disorders
  • pathology of the feet, ankles, hips, or opposite knee causing significant pain or gait alterations
  • Patients who ultimately required a total knee arthroplasty (valgus greater than 14 degree, multiple compartment osteoarthritis were contraindications to unicondylar knee arthroplasty.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Leelasestaporn C, Tarnpichprasert T, Arirachakaran A, Kongtharvonskul J. Comparison of 1-year outcomes between MAKO versus NAVIO robot-assisted medial UKA: nonrandomized, prospective, comparative study. Knee Surg Relat Res. 2020 Mar 12;32(1):13. doi: 10.1186/s43019-020-00030-x.

MeSH Terms

Conditions

Osteoarthritis, Knee

Condition Hierarchy (Ancestors)

OsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: prospective cohort study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principle investigator

Study Record Dates

First Submitted

May 13, 2019

First Posted

May 17, 2019

Study Start

June 1, 2015

Primary Completion

January 1, 2018

Study Completion

January 1, 2018

Last Updated

June 20, 2019

Record last verified: 2019-06