Blood Pressure in the Emergency Department

NCT03954119 | Completed

• 1 other identifier: BPED1605
• Study Type: observational
• Target: 300,272
• Locations: 0 countries
• Sites: N/A

Brief Summary

This is a cohort study based on a large sample (\> 600 000) of emergency department (ED) visits from two university hospital EDs. Information on incident disease after discharge from the ED will be collected through linkage to Swedish national in-patient register and cause of death register. The importance of blood pressure measured at the ED for incident atherosclerotic cardiovascular disease during long term follow up will be studied by Cox-regression analysis

Conditions

Blood Pressure; Hypertension; Emergencies

Keywords

blood pressure; emergency department; atherosclerotic cardiovascular disease; myocardial infarction; stroke; long-term prognosis

Outcome Measures

Primary Outcomes (1)

• Incident Atherosclerotic Cardiovascular Disease (ASCVD)

  ASCVD was defined as a combination of fatal coronary heart disease (CHD ), (I210-I214, I219, I220, I221, I228, I229, I461 or I469), non-fatal MI (I210-I214, I219, I220, I221, I228 or I229), fatal and non-fatal ischemic stroke (I630-I635, I638 or I639). According to the International Classification of Diseases 10th edition (ICD-10).

  20161231

Secondary Outcomes (4)

• Incident Myocardial infarction (MI)

  2016-12-31

• Incident All-cause stroke

  2016-12-31

• Incident Heart failure

  2016-12-31

• Incident chronic kidney disease (CKD)

  2016-12-31

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Unselected adult patients attending the ED irrespective of chief complaint

You may qualify if:

• Attending the Emergency departments (ED) at Karolinska University hospital in Solna or Huddinge during the specified time period
• Record of blood pressure measurement from the ED-visit

Sponsors & Collaborators

• Karolinska Institutet: lead

Related Publications (1)

• Oras P, Habel H, Skoglund PH, Svensson P. Elevated Blood Pressure in the Emergency Department: A Risk Factor for Incident Cardiovascular Disease. Hypertension. 2020 Jan;75(1):229-236. doi: 10.1161/HYPERTENSIONAHA.119.14002. Epub 2019 Dec 2.

  PMID: 31786971 DERIVED

MeSH Terms

Conditions

Hypertension; Emergencies; Atherosclerosis; Myocardial Infarction; Stroke

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Arteriosclerosis; Arterial Occlusive Diseases; Myocardial Ischemia; Heart Diseases; Infarction; Ischemia; Necrosis; Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases

Study Officials

• Per O Svensson, MD PhD

  Department of Clinical Science and Education, Södersjukhuset |

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate professor

Study Record Dates

• First Submitted: May 15, 2019
• First Posted: May 17, 2019
• Study Start: January 1, 2009
• Primary Completion: March 31, 2016
• Study Completion: March 31, 2016
• Last Updated: May 20, 2019

Record last verified: 2019-05