NCT03947554

Brief Summary

This study evaluates the effects of a specific herbal preparation of Panax ginseng in preventing symptoms of stress in healthy individuals.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P50-P75 for phase_1

Timeline
Completed

Started Apr 2019

Shorter than P25 for phase_1

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2019

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

May 9, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 13, 2019

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2019

Completed
16 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2019

Completed
Last Updated

July 5, 2019

Status Verified

May 1, 2019

Enrollment Period

3 months

First QC Date

May 9, 2019

Last Update Submit

July 2, 2019

Conditions

Keywords

Panax ginsengRed ginsengKorean ginsengAdaptogen

Outcome Measures

Primary Outcomes (1)

  • Change in Perceived Stress Scale (PSS) from baseline to the last day of treatment

    The Perceived Stress Scale is a psychological instrument for measuring the perception of stress by an individual. Scores from 0-13 indicate low stress, 14-26 is considered moderate stress, and scores from 27-40 indicate high perceived stress. The primary outcome is the change in the baseline PSS score for HRG80 versus standard Panax ginseng and placebo.

    Two weeks

Study Arms (3)

HRG80 Panax ginseng

EXPERIMENTAL

Panax ginseng standardized to 63.4 mg of total ginsenosides taken orally once daily in the morning after a meal.

Dietary Supplement: HRG80 Panax ginseng

Panax ginseng

ACTIVE COMPARATOR

Panax ginseng standardized to 19.6 mg of total ginsenosides taken orally once daily in the morning after a meal.

Dietary Supplement: Panax ginseng

Placebo

PLACEBO COMPARATOR

Placebo capsule containing brown sugar and rice flour, taken orally once daily in the morning after a meal.

Dietary Supplement: Placebo

Interventions

HRG80 Panax ginsengDIETARY_SUPPLEMENT

Panax ginseng containing 63.4 mg ginsenosides

HRG80 Panax ginseng
Panax ginsengDIETARY_SUPPLEMENT

Panax ginseng containing 19.6 mg ginsenosides

Panax ginseng
PlaceboDIETARY_SUPPLEMENT

800 mg excipient

Placebo

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Individuals experiencing at least one symptom of stress and fatigue during 8 hours of mental work with a computer.
  • Men and women ages 18-65 (all races and ethnicities)
  • Able to understand and participate in an 11-week study

You may not qualify if:

  • Taking medicine or dietary supplements which may have potential effects on cognitive function
  • Consuming more than 1 cup of coffee daily (in the morning).

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Sports Medicine and Anti-Doping Service Republican Centre

Yerevan, Armenia

Location

MeSH Terms

Conditions

Stress, Psychological

Interventions

Asian ginseng

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Study Officials

  • Areg Hovhannisyan, PhD, Dr Sci

    Sports Medicine and Anti-Doping Service Republican Centre

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, CARE PROVIDER
Purpose
PREVENTION
Intervention Model
CROSSOVER
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 9, 2019

First Posted

May 13, 2019

Study Start

April 1, 2019

Primary Completion

June 15, 2019

Study Completion

July 1, 2019

Last Updated

July 5, 2019

Record last verified: 2019-05

Locations