Danish Cardiovascular Screening Trial II
DANCAVAS-II
1 other identifier
interventional
38,000
1 country
4
Brief Summary
This study attempts to reduce social inequality in cardiovascular health by performing an interventional screening trial on how best to decrease cardiovascular disease (CVD) among people with low social status.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for not_applicable
Started Aug 2017
Longer than P75 for not_applicable
4 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2017
CompletedFirst Submitted
Initial submission to the registry
February 27, 2018
CompletedFirst Posted
Study publicly available on registry
May 10, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
August 1, 2027
ExpectedFebruary 26, 2025
February 1, 2025
3 years
February 27, 2018
February 22, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Overall mortality
Deaths of any cause
5 years
Study Arms (2)
Screening
ACTIVE COMPARATORInvitation to cardiovascular screening
Control
PLACEBO COMPARATORNo invitation to cardiovascular screening
Interventions
Invitation to CVD screening with non contrast CT scanning, ABI measurement and blood tests
Eligibility Criteria
You may qualify if:
- Men aged 60-64 living in the municipalities of Funen, Silkeborg, Vejle and surrounding municipailties
You may not qualify if:
- Men not aged 60-64
- Men not living in the mentioned municipalities
- Women
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Odense University Hospitallead
- University of Aarhuscollaborator
Study Sites (4)
Odense University Hospital
Odense, 5000, Denmark
Region Hospital Silkeborg
Silkeborg, 8600, Denmark
Svendborg Sygehus
Svendborg, 5700, Denmark
Vejle Sygehus
Vejle, 7100, Denmark
Related Publications (2)
Lindholt JS, Mejldal A, Rasmussen LM, Lambrechtsen J, Steffensen FH, Frost L, Egstrup K, Urbonaviciene G, Busk M, Karon M, Diederichsen ACP. Outcomes of cardiovascular screening in men aged 60-64 years: the DANCAVAS II trial. Eur Heart J. 2025 Aug 30:ehaf704. doi: 10.1093/eurheartj/ehaf704. Online ahead of print.
PMID: 40884758DERIVEDKhurrami L, Moller JE, Lindholt JS, Urbonaviciene G, Steffensen FH, Lambrechtsen J, Karon M, Frost L, Busk M, Egstrup K, Fredgart MH, Diederichsen ACP. Cross-sectional study of aortic valve calcification and cardiovascular risk factors in older Danish men. Heart. 2021 Oct;107(19):1536-1543. doi: 10.1136/heartjnl-2021-319023. Epub 2021 Aug 10.
PMID: 34376488DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jes S Lindholt, PhD
Odense University Hospital
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- SCREENING
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor of Vascular Surgery
Study Record Dates
First Submitted
February 27, 2018
First Posted
May 10, 2019
Study Start
August 1, 2017
Primary Completion
August 1, 2020
Study Completion (Estimated)
August 1, 2027
Last Updated
February 26, 2025
Record last verified: 2025-02
Data Sharing
- IPD Sharing
- Will not share
Not possible due to data are stored and analysed in the platform of Statistics Denmark