Recovery of Performance, Muscle Damage and Neuromuscular Fatigue Following Muscle Power Training

NCT03936595 | Terminated

• 1 other identifier: Power Training-Recovery UTH
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

Muscle power is one of the most important parameters in almost every athletic action, and expresses the ability of the human muscle to produce great amounts of force with the greatest possible speed. Thus, muscle power is critical for high performance in athletic actions such as jumping, throwing, change of direction and sprinting. For enhancing their muscle power, athletes comprise several resistance training programs as part of their training. Muscle power training comprises of eccentric muscle actions, and the magnitude of these actions depend on the emphasis that is given on the concentric or eccentric action, respectively, of the muscles during the exercises. However, eccentric muscle action, especially when unaccustomed, can lead to exercise-induced muscle damage (EIMD), and deterioration of muscle performance. Despite the fact that muscle power training comprises eccentric muscle actions, and consequently can lead to muscle injury and muscle performance reduction during the following days, the recovery kinetics after acute muscle power training have not been adequately studied. However, information regarding the recovery of the muscles after a power training protocol, is critical for the correct design of a training microcycle, and the reduction of injury risk. The aim of the present study is to investigate the muscle injury provoked after acute muscle power training using three different power training exercise protocols. Additionally, we will examine the effect of these protocols on muscle performance and neuromuscular fatigue indices.

Conditions

Power Training Exercise Protocols

Outcome Measures

Primary Outcomes (10)

• Change on delayed onset of muscle soreness (DOMS), in the knee flexors (KF) and extensors (KE) of both limbs

  Participants will perform three repetitions of a full squat movement, and rate their soreness level in knee flexors and extensors on a visual analog scale from 1 to 10 (VAS, with "no pain" at one end and "extremely sore" at the other), using palpation of the belly and the distal region of relaxed knee extensors and flexors.

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change on countermovement jump (CMJ) height

  CMJ height will be measured in 3 maximal efforts (the best jump will be recorded) on an Ergojump contact platform

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change on isometric peak torque of the knee extensors (KE)

  Isometric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change on isometric peak torque of the knee flexors (KF)

  Isometric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change on concentric isokinetic peak torque of the knee extensors (KE)

  Concentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change on concentric isokinetic peak torque of the knee flexors (KF)

  Concentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change one eccentric isokinetic peak torque of the knee extensors (KE)

  Eccentric peak torque of the KE will be measured on an isokinetic dynamometer at 60◦/sec

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change on eccentric isokinetic peak torque of the knee flexors (KF)

  Eccentric peak torque of the KF will be measured on an isokinetic dynamometer at 60◦/sec

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change on the concentration of plasma CK activity

  Plasma CK activity will be measured with a biochemical analyzer

  Prior to, immediately after, 1, 2, 3 days after the end of the experimental protocol

• Change on the concentration of blood lactate

  Lactate will be measured with a portable lactate analyzer using capillary blood

  Prior to, and immediately after the end of the experimental protocol

Study Arms (4)

Core exercises protocol

EXPERIMENTAL

Participants will perform 4 core exercises

Other: Core exercises protocol

Structural exercises protocol

EXPERIMENTAL

Participants will perform 4 structural (Olympic lifting) exercises

Other: Structural exercises protocol

Accentuated eccentric load exercises protocol

EXPERIMENTAL

Participants will perform 4 exercises with eccentric loading

Other: Accentuated eccentric load exercises protocol

Control condition

OTHER

Participants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol

Other: Control condition

Interventions

Core exercises protocol OTHER

Participants will perform: 1. Squats, 4 sets of 5 repetitions at 60% 1RM 2. Deadlifts, 4 sets of 5 repetitions at 60% 1RM 3. Lunges, 4 sets of 5 repetitions at 60% 1RM 4. Step ups, 4 sets of 5 repetitions at 60% 1RM

Core exercises protocol

Structural exercises protocol OTHER

Participants will perform: 1. Snatch, 4 sets of 5 repetitions at 60% 1RM 2. Hang clean, 4 sets of 5 repetitions at 60% 1RM 3. Push jerk, 4 sets of 5 repetitions at 60% 1RM 4. Split push jerk, 4 sets of 5 repetitions at 60% 1RM

Structural exercises protocol

Accentuated eccentric load exercises protocol OTHER

Participants will perform: 1. Deadlifts - squat jump, 4 sets of 5 repetitions at 30% body mass (BM) 2. Step down - squat jump, 4 sets of 5 repetitions at 30% BM 3. Step down - lunges, 4 sets of 5 repetitions at 30% BM 4. Hip thrusts, 4 sets of 5 repetitions at 30% BM

Accentuated eccentric load exercises protocol

Control condition OTHER

Participants will perform all the measurements that are comprised in the experimental conditions without performing any exercise protocol

Control condition

Eligibility Criteria

• Age: 18 Years - 35 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• No recent history of musculoskeletal injury
• No use of ergogenic supplements and drugs
• No use of anti-inflammatory and antioxidant supplements (\> 6 months)
• No participation at intense eccentric exercise for at least 3 days before protocols

You may not qualify if:

• Recent history of musculoskeletal injury
• Use of ergogenic supplements and drugs
• Use of anti-inflammatory and antioxidant supplements (\< 6 months)
• Participation at intense eccentric exercise for at least 3 days before protocols

Sponsors & Collaborators

• University of Thessaly: lead

Study Sites (1)

Laboratory of Exercise Biochemistry, Exercise Physiology,and Sports Nutrition, School of Physical Education and Sport Science, University of Thessaly

Trikala, Thessaly, 42100, Greece

Location

Related Publications (6)

• Cormie P, McCaulley GO, Triplett NT, McBride JM. Optimal loading for maximal power output during lower-body resistance exercises. Med Sci Sports Exerc. 2007 Feb;39(2):340-9. doi: 10.1249/01.mss.0000246993.71599.bf.

  PMID: 17277599 BACKGROUND

• Baird MF, Graham SM, Baker JS, Bickerstaff GF. Creatine-kinase- and exercise-related muscle damage implications for muscle performance and recovery. J Nutr Metab. 2012;2012:960363. doi: 10.1155/2012/960363. Epub 2012 Jan 11.

  PMID: 22288008 BACKGROUND

• Deli CK, Fatouros IG, Paschalis V, Georgakouli K, Zalavras A, Avloniti A, Koutedakis Y, Jamurtas AZ. A Comparison of Exercise-Induced Muscle Damage Following Maximal Eccentric Contractions in Men and Boys. Pediatr Exerc Sci. 2017 Aug;29(3):316-325. doi: 10.1123/pes.2016-0185. Epub 2017 Feb 6.

  PMID: 28165870 BACKGROUND

• Jamurtas AZ, Theocharis V, Tofas T, Tsiokanos A, Yfanti C, Paschalis V, Koutedakis Y, Nosaka K. Comparison between leg and arm eccentric exercises of the same relative intensity on indices of muscle damage. Eur J Appl Physiol. 2005 Oct;95(2-3):179-85. doi: 10.1007/s00421-005-1345-0. Epub 2005 Jul 9.

  PMID: 16007451 BACKGROUND

• Kyrolainen H, Avela J, McBride JM, Koskinen S, Andersen JL, Sipila S, Takala TE, Komi PV. Effects of power training on muscle structure and neuromuscular performance. Scand J Med Sci Sports. 2005 Feb;15(1):58-64. doi: 10.1111/j.1600-0838.2004.00390.x.

  PMID: 15679573 BACKGROUND

• Walker S, Blazevich AJ, Haff GG, Tufano JJ, Newton RU, Hakkinen K. Greater Strength Gains after Training with Accentuated Eccentric than Traditional Isoinertial Loads in Already Strength-Trained Men. Front Physiol. 2016 Apr 27;7:149. doi: 10.3389/fphys.2016.00149. eCollection 2016.

  PMID: 27199764 BACKGROUND

Study Officials

• Ioannis G Fatouros, PhD

  University of Thessaly

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: Each participant will perform in a random order all four different experimental conditions

Study Record Dates

• First Submitted: April 30, 2019
• First Posted: May 3, 2019
• Study Start: May 6, 2019
• Primary Completion: June 16, 2019
• Study Completion: June 28, 2019
• Last Updated: January 5, 2021

Record last verified: 2020-12

Locations

GR (1)