NCT03931759

Brief Summary

The Effect of Intra-abdominal Pressure

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
130

participants targeted

Target at P50-P75 for not_applicable diabetes-mellitus

Timeline
Completed

Started Jun 2019

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 23, 2019

Completed
7 days until next milestone

First Posted

Study publicly available on registry

April 30, 2019

Completed
1 month until next milestone

Study Start

First participant enrolled

June 1, 2019

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2020

Completed
Last Updated

May 2, 2019

Status Verified

April 1, 2019

Enrollment Period

1 year

First QC Date

April 23, 2019

Last Update Submit

April 30, 2019

Conditions

Keywords

diabetes mellituscardiac autonomic neuropathylaparoscopic surgery

Outcome Measures

Primary Outcomes (1)

  • The measurement of heart rate variability in laparoscopic surgeries

    The measurement of heart rate variability is used as a method to assess the autonomic nerve system. As the autonomic nerve system dysfunction may complicate the possible peroperative problems in the patients to be operated, the pre-assessment of the autonomic nerve system function should be considered as an acquisition required to be obtained in the daily anesthesia practice. When we increase the intraabdominal pressure during the laparoscopic surgery, we think that the hemodynamic responses of the diabetic patient group, especially the patients with autonomic neuropathy, to this increasing intraabdominal pressure will be different. The aim of the present study is to investigate the effect of the intraabdominal pressure, applied to the patients diagnosed with diabetes mellitus who will have laparoscopic surgery, on hemodynamics.

    1 year

Study Arms (2)

Diabetes mellitus

ACTIVE COMPARATOR

patients with diabetes mellitus

Diagnostic Test: laparoscopic surgery

non-Diabetes mellitus

NO INTERVENTION

patients without diabetes mellitus

Interventions

laparoscopic surgeryDIAGNOSTIC_TEST

patients with diabetes mellitus in laparoscopic surgery

Also known as: hearth rate variability
Diabetes mellitus

Eligibility Criteria

Age40 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • diabetes mellitus
  • laparoscopic surgery

You may not qualify if:

  • hypertension
  • hearth failure
  • renal failure
  • hepatic failure
  • difficult intubation
  • shock

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Diabetes MellitusAsthma, Nasal Polyps, And Aspirin Intolerance

Interventions

Laparoscopy

Condition Hierarchy (Ancestors)

Glucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Intervention Hierarchy (Ancestors)

EndoscopyDiagnostic Techniques, SurgicalDiagnostic Techniques and ProceduresDiagnosisMinimally Invasive Surgical ProceduresSurgical Procedures, Operative

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SCREENING
Intervention Model
CROSSOVER
Model Details: prospective randomize clinical trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
research assistant

Study Record Dates

First Submitted

April 23, 2019

First Posted

April 30, 2019

Study Start

June 1, 2019

Primary Completion

June 1, 2020

Study Completion

June 1, 2020

Last Updated

May 2, 2019

Record last verified: 2019-04

Data Sharing

IPD Sharing
Will not share