NCT03920436

Brief Summary

The investigators conduct a randomized, double-blind, placebo-controlled study to investigate the effects of oral ingestion of drinking water using a tumbler that emits far infrared rays at room temperature on metabolic profile in adults for 8 weeks.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Feb 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 1, 2019

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

April 16, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 18, 2019

Completed
2 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

July 31, 2019

Completed
Last Updated

September 11, 2019

Status Verified

September 1, 2019

Enrollment Period

5 months

First QC Date

April 16, 2019

Last Update Submit

September 10, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Low density lipoprotein cholesterol (LDL-C)

    Change of LDL-C during 8 weeks

    Change from baseline level of LDL-C at 8 weeks

Secondary Outcomes (6)

  • aspartate transaminase (AST)

    Change from baseline level of AST at 8 weeks

  • creatinine

    Change from baseline level of creatinine at 8 weeks

  • homeostasis model assessment of insulin resistance (HOMA-IR)

    Change from baseline level of HOMA-IR at 8 weeks

  • body weight

    Change from baseline level at 8 weeks

  • free fatty acid

    Change from baseline level at 8 weeks

  • +1 more secondary outcomes

Study Arms (2)

Infrared water group

EXPERIMENTAL

This group takes drinking water using a tumbler that emits far infrared rays at room temperature for 8 weeks.

Dietary Supplement: infrared water group

sham group

SHAM COMPARATOR

This group takes drinking water using a tumbler at room temperature for 8 weeks.

Dietary Supplement: sham group

Interventions

infrared water groupDIETARY_SUPPLEMENT

This group takes 1,8 L of drinking water using a tumbler that emits far infrared rays at room temperature.

Infrared water group
sham groupDIETARY_SUPPLEMENT

This group takes 1,8 L of drinking water using a tumbler at room temperature.

sham group

Eligibility Criteria

Age19 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years and older

You may not qualify if:

  • aspartate aminotransferase (AST) or alanine aminotransferase (ALT) more than twice the highest reference value
  • serum creatinine ≥ 1.5 mg/dL)
  • uncontrolled diabetes mellitus (a fasting glucose of \>160 mg/dL)
  • uncontrolled hypertension (BP \> 160/100 mmHg)
  • severe gastrointestinal symptoms
  • alcohol abuser
  • pregnant or lactating women
  • allergic to the ingredient involved
  • cardiocebrovascular diseases or any cancer during the six months prior to study
  • smoker

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pusan National University Yangsan Hospital

Yangsan, Gyeungsangnam-do, 50612, South Korea

Location

Study Officials

  • Sang Yeoup Lee

    Pusan National University Yangsan Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor of Family Medicine

Study Record Dates

First Submitted

April 16, 2019

First Posted

April 18, 2019

Study Start

February 1, 2019

Primary Completion

July 1, 2019

Study Completion

July 31, 2019

Last Updated

September 11, 2019

Record last verified: 2019-09

Locations