NCT03919136

Brief Summary

In this study, the investigators are testing the accuracy of a wrist-worn measurement device by comparing its blood pressure measurement to arterial line (A-line) blood pressure monitors. The device is similar in style and fit to popular activity bands, but it is unique in that it measures blood pressure.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
40

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Aug 2018

Geographic Reach
1 country

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2018

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

April 15, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 18, 2019

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2019

Completed
Last Updated

April 19, 2019

Status Verified

April 1, 2019

Enrollment Period

1.2 years

First QC Date

April 15, 2019

Last Update Submit

April 17, 2019

Conditions

Keywords

Heart FailureAdvanced Heart FailureBlood PressureHigh Blood PressureLow Blood Pressure

Outcome Measures

Primary Outcomes (1)

  • Non-Oscillometric Blood Pressure Wrist Worn Data Acquisition and Analysis

    Measurements including systolic and diastolic pressures will be assessed and analyzed retrospectively according to the requirements of the standard (ISO 81060-2).

    2 years

Study Arms (1)

Primary Objective

Evaluation of the devices accuracy referenced to interventional (A-line) measurement.

Device: Wrist-worn measurement device (LiveMetric)

Interventions

Evaluation of the wrist-worn measurement devices accuracy referenced to interventional (A-line) measurements.

Primary Objective

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with an arterial line used for continuous blood pressure monitoring.

You may qualify if:

  • Patients who have a pre-existing intra-arterial blood pressure (A-Line) line for standard care
  • Patients that are ≥18 years of age.

You may not qualify if:

  • Body habitus that precludes patients from wearing a device on their wrist
  • Subjects without normal palpable radial artery pulse, whether congenital, due to medical intervention, or otherwise
  • Subjects with wrist circumference less than 155mm or greater than 210mm
  • Subjects implanted with pacemaker, VAD's or other mechanical circulatory support device whether intracorporeal or extracorporeal
  • Patients that do not have an intra-arterial blood pressure line.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

University of Chicago

Chicago, Illinois, 606037, United States

RECRUITING

Northwestern Memorial Hospital

Chicago, Illinois, 60611, United States

RECRUITING

NYU School of Medicine

New York, New York, 10016, United States

RECRUITING

Related Publications (1)

  • Sayer G, Piper G, Vorovich E, Raikhelkar J, Kim GH, Rodgers D, Shimbo D, Uriel N. Continuous Monitoring of Blood Pressure Using a Wrist-Worn Cuffless Device. Am J Hypertens. 2022 May 10;35(5):407-413. doi: 10.1093/ajh/hpac020.

MeSH Terms

Conditions

Heart FailureHypertensionHypotension

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Gabriel Sayer, MD

    University of Chicago

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 15, 2019

First Posted

April 18, 2019

Study Start

August 1, 2018

Primary Completion

October 1, 2019

Study Completion

October 1, 2019

Last Updated

April 19, 2019

Record last verified: 2019-04

Data Sharing

IPD Sharing
Will not share

Locations