NCT03914339

Brief Summary

The main aim of this prospective, randomized controlled clinical study is to: • To evaluate and compare the effect of a combined orthodontic -periodontal treatment protocol versus periodontal treatment alone on osseous and non -osseous parameters in periodontally compromised patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
36

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Dec 2018

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 1, 2018

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

April 11, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

April 16, 2019

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 1, 2020

Completed
Last Updated

April 16, 2019

Status Verified

April 1, 2019

Enrollment Period

1.3 years

First QC Date

April 11, 2019

Last Update Submit

April 11, 2019

Conditions

Outcome Measures

Primary Outcomes (2)

  • • Alveolar crest bone level

    measured from Cemento- enamel junction to bone crest.

    12 months

  • Clinical attachment level (CAL).

    • pocket to cemento- enamel junction .

    12 months

Study Arms (2)

Test group

EXPERIMENTAL

Eighteen periodontally compromised patients who will be given both orthodontic and periodontal treatment .

Procedure: Periodontal and orthodontic treatment

control group

ACTIVE COMPARATOR

Eighteen periodontally compromised patients will receive periodontal treatment alone .

Procedure: periodontal treatment

Interventions

Eighteen periodontally compromised patients who give be given both periodontal and orthodontic treatment

Test group

Eighteen periodontally compromised patients who give be given periodontal treatment alone.

control group

Eligibility Criteria

Age20 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Patient age criteria 20-40 years.
  • Periodontally Compromised dentition with moderate to severe periodontitis ≥2 teeth with pocket depth (PD) ≥5 mm and loss of clinical attachment level (CAL) ≥ 4mm. and radiographic bone loss
  • Good general health status.
  • Malocclusion that needs orthodontic treatment

You may not qualify if:

  • Systemic illness known to affect the periodontium or outcome of periodontal and orthodontic therapy.
  • Patient taking medications such as corticosteroids or calcium channel blockers, which are known to interfere periodontal wound healing or patient on long term NSAID therapy.
  • Pregnant or lactating women.
  • Smokers(≥5 cigarettes∕ day).
  • Noncompliance to oral hygiene measures after Phase I therapy.
  • Presence of trauma from occlusion (TFO).
  • Patients with aggressive periodontitis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Pgids,Rohtak

Rohtak, Haryana, 124001, India

RECRUITING

PGIDS

Rohtak, Haryana, 124001, India

RECRUITING

MeSH Terms

Conditions

Alveolar Bone Loss

Interventions

OrthodonticsPeriodontal Index

Condition Hierarchy (Ancestors)

Bone ResorptionBone DiseasesMusculoskeletal DiseasesPeriodontal AtrophyPeriodontal DiseasesMouth DiseasesStomatognathic Diseases

Intervention Hierarchy (Ancestors)

DentistryDental Health SurveysHealth SurveysSurveys and QuestionnairesData CollectionEpidemiologic MethodsInvestigative TechniquesPeriodonticsHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public HealthPublic Health Dentistry

Study Officials

  • Rekha sharma, MDS

    PGIDS,ROHTAK

    STUDY CHAIR

Central Study Contacts

Rekha sharma, MDS

CONTACT

meenu gehlot, BDS

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 11, 2019

First Posted

April 16, 2019

Study Start

December 1, 2018

Primary Completion

April 1, 2020

Study Completion

April 1, 2020

Last Updated

April 16, 2019

Record last verified: 2019-04

Locations