NCT03908931

Brief Summary

The purpose of this study is to evaluate the clinical results and MRI imaging of autologous cartilage reconstructions or collagen matrix of the knee. There is currently little data in the literature on clinical outcomes and imaging of this type of lesion.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
130

participants targeted

Target at P50-P75 for not_applicable

Timeline
111mo left

Started Apr 2019

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress44%
Apr 2019Jun 2035

Study Start

First participant enrolled

April 1, 2019

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2019

Completed
4 days until next milestone

First Submitted

Initial submission to the registry

April 5, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 9, 2019

Completed
16.2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2035

Expected
Last Updated

March 17, 2026

Status Verified

March 1, 2026

Enrollment Period

Same day

First QC Date

April 5, 2019

Last Update Submit

March 16, 2026

Conditions

Osteochondral Defect

Outcome Measures

Primary Outcomes (2)

  • Postoperative knee function assessed by clinical examination

    2 years post surgery

  • Postoperative knee function assessed by scores

    2 years post surgery

Study Arms (1)

MRI

EXPERIMENTAL
Radiation: MRI

Interventions

MRIRADIATION

Follow up of osteochondral surgery by MRI and clinical examination

MRI

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • cartilaginous reconstruction by autologous transplant or collagenous chondro-inducing knee matrix
  • \> 18 years

You may not qualify if:

  • Other cartilaginous reconstruction techniques,
  • other than knee joint

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CH de Versailles

Le Chesnay, France

RECRUITING

Central Study Contacts

Nicolas PUJOL

CONTACT

+33139639565npujol@ch-versailles.fr

Laure Morisset

CONTACT

+33139239785lmorisset@ch-versailles.fr

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

April 5, 2019

First Posted

April 9, 2019

Study Start

April 1, 2019

Primary Completion

April 1, 2019

Study Completion (Estimated)

June 1, 2035

Last Updated

March 17, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)