NCT03906110

Brief Summary

The purpose of this study is to test if including personalization in education materials about colorectal cancer screening is more effective at helping encourage people to complete colorectal cancer screening.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
327

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2018

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 3, 2018

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

April 4, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 8, 2019

Completed
3.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 26, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 26, 2022

Completed
Last Updated

April 20, 2023

Status Verified

April 1, 2023

Enrollment Period

4.1 years

First QC Date

April 4, 2019

Last Update Submit

April 17, 2023

Conditions

Keywords

Colorectal Cancer ScreeningFIT testFecal Immunochemical Test

Outcome Measures

Primary Outcomes (3)

  • Fecal Immunochemical Test (FIT) use -Time Point 1

    Participants use of FIT kits will be measured based on FIT sample return rate.

    Time Point 1 (at 3 months)

  • Fecal Immunochemical Test (FIT) Use- Time Point 2

    Participants use of FIT kits will be measured based on FIT sample return rate.

    Time Point 2 (up to 18 months)

  • Fecal Immunochemical Test (FIT) Use- Time Point 3

    Participants long term FIT adherence will be measured based on FIT sample return rate.

    Time Point 3 (End of study, up to 30 months)

Study Arms (2)

C-Cares

Participants will be given Community Colorectal Cancer Awareness, Research, Education and Screening (C-CARES) Materials and FIT kits.

Behavioral: Community Colorectal Cancer Awareness, Research, Education & Screening (C-CARES) MaterialsBehavioral: Contact MessageDiagnostic Test: Fecal Immunochemical Test (FIT)

C-Cares Plus

Participants will be given Community Colorectal Cancer Awareness, Research, Education and Screening (C-CARES) materials, FIT kits, and personalized one-on-one education and coaching.

Behavioral: Community Colorectal Cancer Awareness, Research, Education & Screening (C-CARES) MaterialsBehavioral: Contact MessageBehavioral: Personalized One on One EducationDiagnostic Test: Fecal Immunochemical Test (FIT)

Interventions

Educational materials (photonovella +DVD) + Fecal Immunochemical Test (FIT) kit. Offers colorectal cancer screening information using a novella format. Materials describe colorectal cancer and screening tests that are available, and procedures for completing FIT kit.

C-CaresC-Cares Plus
Contact MessageBEHAVIORAL

Card with a general message about colorectal cancer screening. This same message will be delivered at 3 time points.

C-CaresC-Cares Plus

* Trained study coordinators will meet with participant for a brief 15 minute educational session delivered in clinic that summarizes information from the materials and demonstrates FIT collection. * Email or text reminders with brief messages in clear language will be sent that aim to remind and prompt patients to complete FIT. * For participants that are not responsive to above, trained study staff will address specific FIT specific hinderances by telephone or in clinic. * Participants will receive a one page summary of key points of salience of repeat screening "GET FIT AGAIN". Another FIT kit is provided.

C-Cares Plus

The Fecal Immunochemical Test (FIT), is a screening test that detects hemoglobin in stool samples, only requiring one stool sample.

C-CaresC-Cares Plus

Eligibility Criteria

Age50 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Established patients of community health clinics aged 50-75 with average risk of colorectal cancer.

You may qualify if:

  • Able to understand, read and speak English or Spanish
  • Are not up-to-date with colorectal cancer screening
  • No symptoms of colorectal cancer
  • Not at increased risk for colorectal cancer due to family history or personal high-risk GI syndromes

You may not qualify if:

  • Symptoms of colorectal cancer
  • Family history of colorectal cancer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

H. Lee Moffitt Cancer Center and Research Institute

Tampa, Florida, 33612, United States

Location

Related Publications (1)

  • Christy SM, Sutton SK, Abdulla R, Boxtha C, Gonzalez P, Cousin L, Ewing A, Montoya S, Lopez D, Beehler T, Sanchez J, Carvajal R, Meade CD, Gwede CK. A multilevel, low literacy dual language intervention to promote colorectal cancer screening in community clinics in Florida: A randomized controlled trial. Prev Med. 2022 May;158:107021. doi: 10.1016/j.ypmed.2022.107021. Epub 2022 Mar 17.

    PMID: 35305995BACKGROUND

MeSH Terms

Conditions

Colorectal Neoplasms

Interventions

Educational StatusMass Screening

Condition Hierarchy (Ancestors)

Intestinal NeoplasmsGastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteNeoplasmsDigestive System DiseasesGastrointestinal DiseasesColonic DiseasesIntestinal DiseasesRectal Diseases

Intervention Hierarchy (Ancestors)

Socioeconomic FactorsPopulation CharacteristicsDiagnostic Techniques and ProceduresDiagnosisHealth SurveysSurveys and QuestionnairesData CollectionEpidemiologic MethodsInvestigative TechniquesDiagnostic ServicesPreventive Health ServicesHealth ServicesHealth Care Facilities Workforce and ServicesHealth Care Evaluation MechanismsQuality of Health CareHealth Care Quality, Access, and EvaluationPublic HealthEnvironment and Public HealthPublic Health Practice

Study Officials

  • Clement K Gwede, PhD, MPH, RN

    H. Lee Moffitt Cancer Center and Research Institute

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 4, 2019

First Posted

April 8, 2019

Study Start

April 3, 2018

Primary Completion

May 26, 2022

Study Completion

May 26, 2022

Last Updated

April 20, 2023

Record last verified: 2023-04

Data Sharing

IPD Sharing
Will not share

Locations