NCT03897569

Brief Summary

The study will investigate an association between ankle dorsiflexion and altered frontal knee kinematics during step down test in patients with PFPS.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
46

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Mar 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 27, 2019

Completed
3 days until next milestone

Study Start

First participant enrolled

March 30, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

April 1, 2019

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2019

Completed
Last Updated

July 30, 2019

Status Verified

July 1, 2019

Enrollment Period

3 months

First QC Date

March 27, 2019

Last Update Submit

July 28, 2019

Conditions

Keywords

Patellofemoral Pain Syndromeknee kinematicsfrontal projection angleankle motion

Outcome Measures

Primary Outcomes (1)

  • Frontal knee kinematic

    The knee kinematic will be measured by using digital video camera using single leg squat during functional step down test

    20 minutes

Secondary Outcomes (1)

  • Ankle mobility

    20 minutes

Study Arms (2)

patellofemoral pain syndrome

twenty subjects with anterior or retropatellar knee pain from at least 2 of the following Activities : (1) prolonged sitting; (2) stair climbing; (3) squatting; (4) running; (5) kneeling; and (6) hopping/jumping.

Other: frontal projection angle, ankle dorsiflexion

control

twenty-six asymptomatic subject will be recruited for this study and should have no pain or other relevant clinical symptoms in the lower quadrant

Other: frontal projection angle, ankle dorsiflexion

Interventions

Dorsiflexion measurements will be taken in 4 different positions and repeated and recorded 3 times in each position, Prone bent, straight knee and Standing bent, straight knee. Prior to the measurement, the participants completed two 30-second calf stretches The FPPA was determined as the angle at the knee formed by lines connecting the anterior superior iliac spine, the midpoint of the femoral condyles and the midpoint of the malleoli at the deepest part of the squat

controlpatellofemoral pain syndrome

Eligibility Criteria

Age18 Years - 35 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Subjects between 18 to 35 years old with symptomatic patellofemoral pain syndrome and healthy control.

You may qualify if:

  • Anterior or retropatellar knee pain from at least 2 of the following Activities : (1) prolonged sitting; (2) stair climbing; (3) squatting; (4) running; (5) kneeling; and (6) hopping/jumping.
  • Insidious onset of symptoms unrelated to a traumatic incident and persistent for at least 6weeks.
  • VAS equal to or greater than 3.
  • Age of the subject 18-35 years to limit the possibility that PFPS over age 35 may have been complicated by arthritic changes, and also the subjects should have closed epiphyseal growth plates.
  • BMI under 30 kg/m2, both gender
  • For the control group, subjects were recruited to this study if they had:
  • No previous history or diagnosis of knee pathology.
  • No pain with any of the above-mentioned provocative activities.
  • No history of lower limb or spinal pathology.

You may not qualify if:

  • A history of any of the following condition: meniscal or other intraarticular pathologic conditions; cruciate or collateral ligament involvement.
  • A history of traumatic patellar subluxation or dislocation.
  • Previous surgery in the lower extremities within the 12 months prior to participation in the study.
  • Any balance impairments are secondary to a vestibular or neurological disorder or secondary to the use of medication.
  • Any lower limb bony/congenital deformity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Faculty of Physical therapy, Cairo University

Cairo, egypt, Egypt

Location

MeSH Terms

Conditions

Patellofemoral Pain Syndrome

Condition Hierarchy (Ancestors)

Joint DiseasesMusculoskeletal Diseases

Study Officials

  • karima A Hassan, PhD

    Cairo University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
principal investigator

Study Record Dates

First Submitted

March 27, 2019

First Posted

April 1, 2019

Study Start

March 30, 2019

Primary Completion

July 1, 2019

Study Completion

July 1, 2019

Last Updated

July 30, 2019

Record last verified: 2019-07

Data Sharing

IPD Sharing
Will not share

Locations