NCT03891602

Brief Summary

The purpose of this study is to learn about discussion between clinicians and their patients related to lung screening. Survey answers will be collected from both clinicians and their patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
654

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2019

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 22, 2019

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

March 25, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 27, 2019

Completed
3.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 10, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 10, 2023

Completed
1.6 years until next milestone

Results Posted

Study results publicly available

August 23, 2024

Completed
Last Updated

August 23, 2024

Status Verified

August 1, 2024

Enrollment Period

3.8 years

First QC Date

March 25, 2019

Results QC Date

June 26, 2024

Last Update Submit

August 14, 2024

Conditions

Keywords

SmokerMemorial Sloan Kettering Cancer Center

Outcome Measures

Primary Outcomes (1)

  • Key Components of Shared Decision Making Process That Predict Patient-perceived Lung Cancer Screening Decision Quality

    Decisional Quality was measured using the multidimensional Decisional Conflict Scale, a 16-item Likert-response scale that was modified by the investigators for the lung cancer screening context. The total score ranging from 0 to 64. This total score is commonly transformed into a standardized score that falls within a 0 to 100 range. Decisional quality measured on this numeric scale from which lower scores represent lower decisional conflict and, therefore, higher decisional quality. Scores below 25 have been associated with low decisional conflict.

    at baseline (study enrollment)

Study Arms (2)

Clinicians

Primary care clinicians (general internists, family physicians, nurse practitioners, physician assistants) who treat lung cancer screening eligible patients

Behavioral: Primary Care Clinicians' Lung Cancer Screening Survey

Smokers/Former Smokers

Current smoker or former smoker who has quit within the past 15 years

Behavioral: Cataldo Lung Cancer Stigma Scale (Smoking-Related Subscale)Behavioral: Patient Trust in the MedicalBehavioral: Decision Conflict Scale (DCS) - Lung Cancer ScreeningBehavioral: Shared Decision Making Questionnaire (SDM-Q)- PatientBehavioral: Stage of Readiness for Smoking Cessation - Contemplation Ladder

Interventions

Perceived Smoking-Related Stigma will be measured using the 5-item Cataldo Lung Cancer Stigma Scale (Smoking-Related Subscale). The response scale is 1 = strongly disagree, to 4 = strongly agree, and scores range from 5 to 25 (high stigma). Cronbach's alphas were 0.75 to 0.89 in prior studies.

Smokers/Former Smokers

Medical Mistrust will be measured using the 5-item Patient Trust in the Medical Profession Scale.80 The five-point Likert responses measure the extent to which patients perceive their clinician to be honest, caring more about convenience, thorough and careful, and trusted. The range of scores is 5 to 25 (higher mistrust). Reliability and validity have been well established with a Cronbach"s alpha of 0.84.

Smokers/Former Smokers

The DCS is a 16-item Likert-response item scale that has been modified for the lung cancer screening and smoking cessation contexts. The DCS was developed by O"Connor,74-75 and validated in many health decisions including breast cancer screening with Cronbach"s alphas ranging from 0.78 to 0.81. 74-75 Despite its name, the DCS measures more than decision conflict to encompass personal perceptions of perceived decision-making quality such as feeling the choice is informed, values based, and likely to be implemented as well as expressing satisfaction with the decision. 74-75 The DCS is comprised of items with response options ranging from 1 (strongly disagree) to 5 (strongly agree). The items are summed to total scale score with lower scores reflective of higher decision conflict and higher scores reflective of lower decision conflict.

Also known as: DCS
Smokers/Former Smokers

Shared Decision Making Process will be measured from the patient perspective using the 9-item Shared Decision Making Questionnaire (SDM-Q-9),77 which has been validated with a Cronbach"s alpha of 0.94.

Also known as: SDM-Q-9
Smokers/Former Smokers

Among current smokers

Smokers/Former Smokers

Includes items to assess attitudes, barriers, and knowledge of lung cancer screening guidelines.

Clinicians

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

All recruitment will take place at Kaiser Permanente Washington.

You may qualify if:

  • CLINICIANS:
  • Clinician (physician, nurse practitioner, or physician assistant)
  • Practicing in a KPWA primary care clinic
  • Having a patient panel with \>/= 10 lung cancer screening eligible patients
  • PATIENTS (Quantitative Phase):
  • Age 55-80 years
  • \>/= 30 pack-year tobacco smoking history
  • Current smoker or former smoker who has quit within the past 15 years
  • Documented SDM lung cancer screening discussion during a recent clinic visit

You may not qualify if:

  • PATIENTS:
  • Significant comorbidities (Charlson Comorbidity Index \>/=3)
  • Lung cancer diagnosis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kaiser Permanente Washington Health Research Institute

Seattle, Washington, 98101-1466, United States

Location

Related Links

MeSH Terms

Conditions

SmokingTobacco SmokingCigarette SmokingLung Neoplasms

Interventions

Cycloserine

Condition Hierarchy (Ancestors)

BehaviorTobacco UseRespiratory Tract NeoplasmsThoracic NeoplasmsNeoplasms by SiteNeoplasmsLung DiseasesRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

IsoxazolesAzolesHeterocyclic Compounds, 1-RingHeterocyclic CompoundsOxazolidinonesOxazolesSerineAmino Acids, NeutralAmino AcidsAmino Acids, Peptides, and Proteins

Results Point of Contact

Title
Lisa Carter-Bawa, PhD, MPH, APRN, ANP-C, FAAN
Organization
Hackensack Meridian Health

Study Officials

  • Jamie Ostroff, PhD

    Memorial Sloan Kettering Cancer Center

    PRINCIPAL INVESTIGATOR
  • Lisa Carter-Bawa, PhD

    Hackensack Meridian Health

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director | Cancer Prevention Precision Control Institute

Study Record Dates

First Submitted

March 25, 2019

First Posted

March 27, 2019

Study Start

March 22, 2019

Primary Completion

January 10, 2023

Study Completion

January 10, 2023

Last Updated

August 23, 2024

Results First Posted

August 23, 2024

Record last verified: 2024-08

Data Sharing

IPD Sharing
Will share

• Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

Locations