NCT03884738

Brief Summary

The purpose of this study was to investigate effects of different strengthening methods on hamstring muscle group's passive mechanical properties and to investigate this effect's relation with performance changes in healthy individuals. 42 healthy sedentary male participated in this study. Passive mechanical properties and strength of hamstring and quadriceps muscles, flexibility of hamstring muscles, anaerobic explosive strength, reaction time, agility were measured. Participants randomized evenly into one of three groups; eccentric, concentric and neuromuscular electrical stimulation (NMES). After 8 weeks training period, participants were measured again.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2019

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 18, 2019

Completed
3 days until next milestone

First Posted

Study publicly available on registry

March 21, 2019

Completed
Same day until next milestone

Study Start

First participant enrolled

March 21, 2019

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

April 22, 2020

Status Verified

April 1, 2020

Enrollment Period

9 months

First QC Date

March 18, 2019

Last Update Submit

April 20, 2020

Conditions

Keywords

Muscle TonusElasticityElectric Stimulation TherapyPhysical Conditioning, Human

Outcome Measures

Primary Outcomes (1)

  • Passive Mechanical Properties

    Tone, Elasticity and Stiffness evaluation. Evaluated with Myotonometer-3

    Change from baseline passive mechanical properties at 8 weeks

Secondary Outcomes (5)

  • Flexibility Measurement

    Change from baseline flexibility at 8 weeks

  • Muscle Strength Measurement

    Change from baseline muscle strength at 8 weeks

  • Agility Measurement

    Change from baseline agility time at 8 weeks

  • Anaerobic Explosive Power

    Change from baseline anaerobic explosive power at 8 weeks

  • Reaction Time

    Change from baseline reaction time at 8 weeks

Study Arms (3)

Concentric

ACTIVE COMPARATOR

Leg Curl Training

Other: Concentric Exercise

Eccentric

ACTIVE COMPARATOR

Nordic Hamstring Training

Other: Nordic Eccentric exercise

Neuromuscular Electrical Stimulation

ACTIVE COMPARATOR

Stimulation Training

Other: Neuromuscular Electrical Stimulation

Interventions

Leg Curl Machine: 1st week - 1st day is 10 maximum repeat test. 2nd week - 2 days of training - 2 sets of 6 repeats. %60 percent of maximum load. 3rd week - 3 days of training - 3 sets of 6-8 repeats. %60-80 of maximum load. 4th-8th week - 3 days of training - 3 sets of 8-12 repeats. when 3 sets of 12 achieved, load was increased with 2.5kg.

Concentric

1. st week - 1 day - 2 sets of 5 repeats. 2. nd week - 2 days - 2 sets of 6 repeats. 3. rd week - 3 days - 3 sets of 6-8 repeats. 4. th week - 3 days - 3 sets of 8-10 repeats. 5-8th weeks - 3 days - 3 sets of 12-8 repeats. When achieved 3 sets of 12 repeats with full range, speed was increased.

Eccentric

8 weeks, three times per week, 15 minutes of bilateral hamstring stimulation. 100 Hz. frequency, 600 microsecond duration rectangular current

Neuromuscular Electrical Stimulation

Eligibility Criteria

Age18 Years - 30 Years
Sexmale(Gender-based eligibility)
Gender Eligibility Detailsonly male participants were accepted
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • being sedentary

You may not qualify if:

  • Having knee, hip and/or back pain
  • Having a cardiovascular condition/disease
  • History of previous knee and/or hip surgery
  • Having a diagnose of any systemic disease
  • History of previous hamstring injury
  • Being physically active within last year ( Regular activity at least 3 days a week and continuity of at least 2 months was accepted as being physically active)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hacettepe University

Ankara, 06100, Turkey (Türkiye)

Location

Related Publications (6)

  • Ayala F, Sainz de Baranda P, De Ste Croix M, Santonja F. Reproducibility and criterion-related validity of the sit and reach test and toe touch test for estimating hamstring flexibility in recreationally active young adults. Phys Ther Sport. 2012 Nov;13(4):219-26. doi: 10.1016/j.ptsp.2011.11.001. Epub 2012 Jan 23.

    PMID: 23068896BACKGROUND
  • Mentiplay BF, Perraton LG, Bower KJ, Adair B, Pua YH, Williams GP, McGaw R, Clark RA. Assessment of Lower Limb Muscle Strength and Power Using Hand-Held and Fixed Dynamometry: A Reliability and Validity Study. PLoS One. 2015 Oct 28;10(10):e0140822. doi: 10.1371/journal.pone.0140822. eCollection 2015.

    PMID: 26509265BACKGROUND
  • Amiri-Khorasani M, Sahebozamani M, Tabrizi KG, Yusof AB. Acute effect of different stretching methods on Illinois agility test in soccer players. J Strength Cond Res. 2010 Oct;24(10):2698-704. doi: 10.1519/JSC.0b013e3181bf049c.

    PMID: 20168255BACKGROUND
  • Schwesig R, Koke A, Fischer D, Fieseler G, Jungermann P, Delank KS, Hermassi S. Validity and Reliability of the New Handball-Specific Complex Test. J Strength Cond Res. 2016 Feb;30(2):476-86. doi: 10.1519/JSC.0000000000001061.

    PMID: 26815176BACKGROUND
  • Mjolsnes R, Arnason A, Osthagen T, Raastad T, Bahr R. A 10-week randomized trial comparing eccentric vs. concentric hamstring strength training in well-trained soccer players. Scand J Med Sci Sports. 2004 Oct;14(5):311-7. doi: 10.1046/j.1600-0838.2003.367.x.

    PMID: 15387805BACKGROUND
  • Glaviano NR, Langston WT, Hart JM, Saliba S. Influence of patterned electrical neuromuscular stimulation on quadriceps activation in individuals with knee joint injury. Int J Sports Phys Ther. 2014 Dec;9(7):915-23.

    PMID: 25540707BACKGROUND

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Officials

  • tuzun fırat, Assoc. Prof.

    Hacettepe University

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Model Details: randomization into three groups and measurement before and after intervention
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Research Assistant

Study Record Dates

First Submitted

March 18, 2019

First Posted

March 21, 2019

Study Start

March 21, 2019

Primary Completion

December 1, 2019

Study Completion

December 1, 2019

Last Updated

April 22, 2020

Record last verified: 2020-04

Data Sharing

IPD Sharing
Will not share

Locations