NCT03880175

Brief Summary

The HIV/AIDS crisis in Sub-Saharan Africa has left millions of children orphaned. These children, who are potentially infected with HIV themselves, are highly vulnerable and face some serious risks to their health and overall well-being. A variety of health and economic interventions to help orphans and vulnerable children (OVCs) (and the households in which they live) are being carried out in Mozambique by World Education Inc./Bantwana (WEI/B), funded by USAID. The program is known in Portuguese as Força à Comunidade e Crianças or FCC (in English, "Strengthening Family and Communities"). This study will collect survey and administrative data to assess the impact of the FCC program on OVCs and the households in which they live. A baseline survey was administered to define a sample of households and individuals to follow over time through the upcoming follow-up survey and to measure baseline household characteristics. Follow-up data collection will begin in March 2019. It has several components:

  1. 1.Household survey The follow-up survey will provide measurements of the rich set of intermediate and final outcomes for the estimation of treatment effects of the FCC program.
  2. 2.Data collection on HIV testing and school attendance This study will supplement survey-reported HIV testing rates with an objective, administrative measure of HIV testing at health clinics. At the time of the follow-up survey, the survey team will recommend that eligible individuals in the household be tested for HIV at a specified local health clinic. To allow tracking of those who follow through with testing, consenting individuals will be given coupons redeemable for a small financial incentive once they have completed an HIV test.
  3. 3.Informational treatments aimed at raising HIV testing rates To allow insight into the mechanisms through which the FCC program has its effects, this study will provide additional simple treatments in the context of the follow-up survey to explore possible FCC mechanisms: stigma reduction, HIV/AIDS information, and HIV treatment (antiretroviral therapy, or ART) information.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,658

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2017

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2017

Completed
2.2 years until next milestone

First Submitted

Initial submission to the registry

March 15, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

March 19, 2019

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2021

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2021

Completed
Last Updated

August 12, 2021

Status Verified

August 1, 2021

Enrollment Period

4.2 years

First QC Date

March 15, 2019

Last Update Submit

August 11, 2021

Conditions

Outcome Measures

Primary Outcomes (2)

  • Indicator for HIV testing coupon redemption at the household level

    This is a household-level binary variable. It takes value 1 if at least one of a household's coupons is redeemed, and 0 otherwise. The researcher will distribute coupons at the household survey. A subject is eligible for a coupon if s/he is not reported HIV+ and has not had an HIV test within 3 months before the visit. A coupon for an adult will be distributed to themselves. A coupon for a child (age \<18) will be distributed to their primary guardian. Each coupon has a value of 50Mts (0.83 USD) and is valid for 14 days. To redeem a coupon, a coupon holder must show up in the designated clinic and provide proof of testing dated within the coupon-validity window. There is a unique barcode on each coupon to allow the researcher to track the use of each coupon. A coupon will be scanned when distributed and redeemed to link to a subject. The analysis sample for this outcome of interest is all households that have received at least one coupon from the researcher.

    14 days following the date coupons are distributed to a household.

  • Indicator for school attendance at the child-level

    This is an individual-level binary variable. It takes value 1 if a school-aged child (6 -17 years of age) is physically present at school on the date the research staff conducts an unannounced school visit; it takes the value of 0 otherwise. The research team will make an unannounced school visit to check the attendance of all school-aged children in the study sample. All school-aged children will be checked regardless of his or her guardian-reported school attendance status. The study team will visit all public primary and secondary schools located in the study community. All unannounced visits will happen on regular school days. Each child will be checked in all neighboring schools. Each child will only be checked once in one school. The analysis sample of this outcome of interest is all school-aged children living in the study households.

    The time when the research team is conducting the school visit, which lasts 4 to 8 hours in each school

Study Arms (18)

FCC DEB and Anti-stigma

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- direct beneficiaryBehavioral: Anti Stigma Information

FCC DEB and HIV info

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- direct beneficiaryBehavioral: HIV/AIDS Information

FCC DEB and ART info

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- direct beneficiaryBehavioral: ART Information

FCC DEB and HIV-ART info

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- direct beneficiaryBehavioral: HIV/AIDS and ART Information Combined

FCC DEB and high coupon value

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- direct beneficiaryBehavioral: High coupon value

FCC DEB and no info

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- direct beneficiary

FCC non-DEB and Anti-stigma

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- non-direct beneficiaryBehavioral: Anti Stigma Information

FCC non-DEB and HIV info

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- non-direct beneficiaryBehavioral: HIV/AIDS Information

FCC non-DEB and ART info

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- non-direct beneficiaryBehavioral: ART Information

FCC non-DEB and HIV-ART info

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- non-direct beneficiaryBehavioral: HIV/AIDS and ART Information Combined

FCC non-DEB and high coupon value

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- non-direct beneficiaryBehavioral: High coupon value

FCC non-DEB and no info

EXPERIMENTAL
Behavioral: FCC (Força à Comunidade e Crianças) program- non-direct beneficiary

FCC control and Anti-stigma

EXPERIMENTAL
Behavioral: Anti Stigma Information

FCC control and HIV info

EXPERIMENTAL
Behavioral: HIV/AIDS Information

FCC control and ART info

EXPERIMENTAL
Behavioral: ART Information

FCC control and HIV-ART info

EXPERIMENTAL
Behavioral: HIV/AIDS and ART Information Combined

FCC control and High coupon value

EXPERIMENTAL
Behavioral: High coupon value

FCC control and no info

NO INTERVENTION

Interventions

Households are directly linked to the FCC implementing organization

FCC DEB and ART infoFCC DEB and Anti-stigmaFCC DEB and HIV infoFCC DEB and HIV-ART infoFCC DEB and high coupon valueFCC DEB and no info

Households live in FCC implementing communities but are not directly linked to the FCC implementing organization

FCC non-DEB and ART infoFCC non-DEB and Anti-stigmaFCC non-DEB and HIV infoFCC non-DEB and HIV-ART infoFCC non-DEB and high coupon valueFCC non-DEB and no info

Adults in the households are provided anti-stigma information

FCC DEB and Anti-stigmaFCC control and Anti-stigmaFCC non-DEB and Anti-stigma

The households receive information about HIV infection and AIDS

FCC DEB and HIV infoFCC control and HIV infoFCC non-DEB and HIV info
ART InformationBEHAVIORAL

The households receive information about antiretroviral therapy.

FCC DEB and ART infoFCC control and ART infoFCC non-DEB and ART info

The households receive both information about HIV/AIDS and information about antiretroviral therapy.

FCC DEB and HIV-ART infoFCC control and HIV-ART infoFCC non-DEB and HIV-ART info

The HIV testing coupons distributed to households in this group have higher values.

FCC DEB and high coupon valueFCC control and High coupon valueFCC non-DEB and high coupon value

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Households that lives in one of the eligible communities.

You may not qualify if:

  • Households that are not in the eligible communities will not be included in the survey sample.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Lessitala Consultoria e Servicos

Beira, Sofala, Mozambique

Location

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome

Condition Hierarchy (Ancestors)

HIV InfectionsBlood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesSlow Virus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
FACTORIAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

March 15, 2019

First Posted

March 19, 2019

Study Start

January 1, 2017

Primary Completion

March 31, 2021

Study Completion

June 30, 2021

Last Updated

August 12, 2021

Record last verified: 2021-08

Locations