NCT03871192

Brief Summary

In suspected facet joints pain, it is recommended to perform nerve blocks to establish the diagnosis with positive results being and indicator of successful of most permanent treatment of facet pain by rhizolysis. Nevertheless, the usefulness of intraarticular joint injection for diagnosis and prediction of successful neurolysis have been scarcely studied. The main purpose of this trial is to compare both methods, nerve block and intra articular injection, in diagnosis and treatment of facet joints pain.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2018

Typical duration for not_applicable

Geographic Reach
1 country

2 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 15, 2018

Completed
7 months until next milestone

First Submitted

Initial submission to the registry

March 10, 2019

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 12, 2019

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 15, 2019

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2020

Completed
Last Updated

March 15, 2019

Status Verified

March 1, 2019

Enrollment Period

1 year

First QC Date

March 10, 2019

Last Update Submit

March 13, 2019

Conditions

Keywords

FACET JOINTSFACET INJECTIONSNERVE BLOCK

Outcome Measures

Primary Outcomes (1)

  • Pain (VAS score)

    score from no pain (0) to maximum pain (10)

    1 year

Secondary Outcomes (1)

  • Oswestry scale

    1 year

Study Arms (6)

FACET JOINT UNDER CT GUIDANCE

EXPERIMENTAL

Injection of the facet joint under computed tomography guidance

Diagnostic Test: NERVE BLOCK UNDER CT GUIDANCEDiagnostic Test: FACET JOINT UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: NERVE BLOCK UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: FACET JOINT UNDER ULTRASOUND GUIDANCEDiagnostic Test: NERVE BLOCK UNDER ULTRASOUND GUIDANCE

NERVE BLOCK UNDER CT GUIDANCE

ACTIVE COMPARATOR

Injection of the nerve under computed tomography guidance

Diagnostic Test: FACET JOINT UNDER CT GUIDANCEDiagnostic Test: FACET JOINT UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: NERVE BLOCK UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: FACET JOINT UNDER ULTRASOUND GUIDANCEDiagnostic Test: NERVE BLOCK UNDER ULTRASOUND GUIDANCE

FACET JOINT UNDER FLUOROSCOPY GUIDANCE

EXPERIMENTAL

Injection of the facet joint under fluoroscopy guidance

Diagnostic Test: FACET JOINT UNDER CT GUIDANCEDiagnostic Test: NERVE BLOCK UNDER CT GUIDANCEDiagnostic Test: NERVE BLOCK UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: FACET JOINT UNDER ULTRASOUND GUIDANCEDiagnostic Test: NERVE BLOCK UNDER ULTRASOUND GUIDANCE

NERVE BLOCK UNDER FLUOROSCOPY GUIDANCE

ACTIVE COMPARATOR

Injection of the nerve under ultrasound guidance

Diagnostic Test: FACET JOINT UNDER CT GUIDANCEDiagnostic Test: NERVE BLOCK UNDER CT GUIDANCEDiagnostic Test: FACET JOINT UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: FACET JOINT UNDER ULTRASOUND GUIDANCEDiagnostic Test: NERVE BLOCK UNDER ULTRASOUND GUIDANCE

FACET JOINT UNDER ULTRASOUND GUIDANCE

EXPERIMENTAL

Injection of the facet joint under ultrasound guidance

Diagnostic Test: FACET JOINT UNDER CT GUIDANCEDiagnostic Test: NERVE BLOCK UNDER CT GUIDANCEDiagnostic Test: FACET JOINT UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: NERVE BLOCK UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: NERVE BLOCK UNDER ULTRASOUND GUIDANCE

NERVE BLOCK UNDER ULTRASOUND GUIDANCE

ACTIVE COMPARATOR

Injection of the nerve under computed ultrasound guidance

Diagnostic Test: FACET JOINT UNDER CT GUIDANCEDiagnostic Test: NERVE BLOCK UNDER CT GUIDANCEDiagnostic Test: FACET JOINT UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: NERVE BLOCK UNDER FLUOROSCOPY GUIDANCEDiagnostic Test: FACET JOINT UNDER ULTRASOUND GUIDANCE

Interventions

injection of triamcinolone in the facet joint under CT guidance

Also known as: facet joint, ct guidance
FACET JOINT UNDER FLUOROSCOPY GUIDANCEFACET JOINT UNDER ULTRASOUND GUIDANCENERVE BLOCK UNDER CT GUIDANCENERVE BLOCK UNDER FLUOROSCOPY GUIDANCENERVE BLOCK UNDER ULTRASOUND GUIDANCE

injection of triamcinolone around the dorsal ramus under CT guidance

Also known as: posterior ramus, ct guidance
FACET JOINT UNDER CT GUIDANCEFACET JOINT UNDER FLUOROSCOPY GUIDANCEFACET JOINT UNDER ULTRASOUND GUIDANCENERVE BLOCK UNDER FLUOROSCOPY GUIDANCENERVE BLOCK UNDER ULTRASOUND GUIDANCE

injection of triamcinolone in the facet joint under fluoroscopy guidance

Also known as: facet joint, fluoroscopy guidance
FACET JOINT UNDER CT GUIDANCEFACET JOINT UNDER ULTRASOUND GUIDANCENERVE BLOCK UNDER CT GUIDANCENERVE BLOCK UNDER FLUOROSCOPY GUIDANCENERVE BLOCK UNDER ULTRASOUND GUIDANCE

injection of triamcinolone around the dorsal ramus under fluoroscopy guidance

Also known as: posterior ramus, fluoroscopy guidance
FACET JOINT UNDER CT GUIDANCEFACET JOINT UNDER FLUOROSCOPY GUIDANCEFACET JOINT UNDER ULTRASOUND GUIDANCENERVE BLOCK UNDER CT GUIDANCENERVE BLOCK UNDER ULTRASOUND GUIDANCE

injection of triamcinolone in the facet joint under ultrasound guidance

Also known as: facet joint, ultrasound guidance
FACET JOINT UNDER CT GUIDANCEFACET JOINT UNDER FLUOROSCOPY GUIDANCENERVE BLOCK UNDER CT GUIDANCENERVE BLOCK UNDER FLUOROSCOPY GUIDANCENERVE BLOCK UNDER ULTRASOUND GUIDANCE

injection of triamcinolone around the dorsal ramus under ultrasound guidance

Also known as: dorsal ramus, ultrasound guidance
FACET JOINT UNDER CT GUIDANCEFACET JOINT UNDER FLUOROSCOPY GUIDANCEFACET JOINT UNDER ULTRASOUND GUIDANCENERVE BLOCK UNDER CT GUIDANCENERVE BLOCK UNDER FLUOROSCOPY GUIDANCE

Eligibility Criteria

Age18 Years - 79 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Lumbar facet syndrome diagnosed by the referring specialist: Rehabilitation, Traumatology or Neurosurgery 2 -Mechanical low back pain that increases with rotation and flexion-extension, without radicular irradiation.
  • failure of conservative treatment (pharmacological and physical therapy). 4-Symptoms present more than 3 months

You may not qualify if:

  • Previous back surgery and other ablative treatments.
  • Contraindication for the use of corticosteroid or local anesthetic.
  • Uncontrolled acute or chronic medical illness.
  • Pregnancy or lactation.
  • Presence of inflammatory arthropathy or neuropathy.
  • Wounds or skin lesions in the area.
  • Diabetes mellitus.
  • Psychiatric disorders
  • Refusal to participate in the study.
  • Demonstration by imaging techniques of other causes that could justify the symptomatology.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Complejo Hospitalario Universitario Granada

Granada, SPA, 18014, Spain

RECRUITING

Hospital Neuro-Traumatologia

Granada, 1800314, Spain

RECRUITING

Study Officials

  • FERNANDO RUIZSANTIAGO, PhD

    HOSPITAL DE NEURO-TRAUMATOLOGIA GRANADA (VIRGEN DE LAS NIEVES)

    PRINCIPAL INVESTIGATOR

Central Study Contacts

ALBERTO MARTINEZ MARTINEZ, MD

CONTACT

Ana María Del Valle Díaz De La Guardia, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Masking Details
The patients and the evaluator don't know if the injection was performed inside the joint or around the nerve
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: the patients are randomly assigned to intraarticular injection or nerve block
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD, section chief musculoskeletal radiology

Study Record Dates

First Submitted

March 10, 2019

First Posted

March 12, 2019

Study Start

August 15, 2018

Primary Completion

August 15, 2019

Study Completion

August 15, 2020

Last Updated

March 15, 2019

Record last verified: 2019-03

Data Sharing

IPD Sharing
Will share

our idea is to publish the short term results and the long term results in order to influence management of this pathology. Tables and statistical analysis will be available for review and metaanalysis.

Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR
Time Frame
1 to 2 years
Access Criteria
open access

Locations