Effect of Mirror Therapy on Unilateral Neglect for Patients After Stroke
1 other identifier
interventional
21
0 countries
N/A
Brief Summary
This is a single-blinded randomized controlled trial to investigate the effects of mirror therapy (MT), with reference to sham mirror (a glass wall) and control (a covered mirror), in reducing unilateral neglect for patients with stroke in 2 centres.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Jul 2016
Typical duration for not_applicable
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2016
CompletedPrimary Completion
Last participant's last visit for primary outcome
September 30, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2018
CompletedFirst Submitted
Initial submission to the registry
February 21, 2019
CompletedFirst Posted
Study publicly available on registry
February 26, 2019
CompletedFebruary 26, 2019
February 1, 2019
1.2 years
February 21, 2019
February 24, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Unilateral neglect
Behavioural Inattention Test
Change of baseline to 3-week and to follow-up at 6-week
Allocentric and egocentric neglect
Gap Detection Test
Change of baseline to 3-week and to follow-up at 6-week
Functional performance related to unilateral neglect
Catherine Bergego Scale
Change of baseline to 3-week and to follow-up at 6-week
Secondary Outcomes (1)
Upper limb functions
Change of baseline to 3-week and to follow-up at 6-week
Study Arms (3)
Mirror therapy
EXPERIMENTALSham mirror
SHAM COMPARATORCovered mirror
ACTIVE COMPARATORInterventions
A mirror is placed at the midsagittal plane of the patient. The patients in the mirror therapy group watched the mirror illusion of the non-affected arm in the mirror and moved together with the affected arm. The treatment programme for all groups consisted of 12 sessions (4 per week for 3 weeks), each lasting for 30 minutes. The movement practice involved 5 table-top tasks and the patient was instructed to perform as many trials as possible in each session with a maximum of 30 trials per task, giving a total of 150 trials per session. Treatment activities are graded according to the severity of the patient's upper extremity impairment.
A transparent glass wall is placed at the midsagittal plane of the patient. The patients in the sham mirror group watched the movements of the affected arm through the transparent glass wall and moved together with the non-affected arm. The treatment programme for all groups consisted of 12 sessions (4 per week for 3 weeks), each lasting for 30 minutes. The movement practice involved 5 table-top tasks and the patient was instructed to perform as many trials as possible in each session with a maximum of 30 trials per task, giving a total of 150 trials per session. Treatment activities are graded according to the severity of the patient's upper extremity impairment.
A covered mirror is placed at the midsagittal plane of the patient. The patients in the control group watched the movements of the non-affected arm and moved together with the affected arm behind the covered mirror. The treatment programme for all groups consisted of 12 sessions (4 per week for 3 weeks), each lasting for 30 minutes. The movement practice involved 5 table-top tasks and the patient was instructed to perform as many trials as possible in each session with a maximum of 30 trials per task, giving a total of 150 trials per session. Treatment activities are graded according to the severity of the patient's upper extremity impairment.
Eligibility Criteria
You may qualify if:
- ischemic or hemorrhagic stroke, confirmed by medical diagnoses compatible with a unilateral right lesion involvement (i.e. left hemiplegic), exhibited left visual field inattention or unilateral neglect by obtaining a total score of star cancellation subtest in the conventional battery of the Behavioural Inattention Test ≤ 51 (out of 54);
- stroke with onset of neurological condition ≤ 6 months previously;
- have normal or corrected-to-normal visual acuity better than 20/60 (6/18) in the better eye;
- with hemiplegic upper extremity functional levels 3-7 as rated by Functional Test for the Hemiplegic Upper Extremity and is able to move against gravity;
- ability to understand and follow simple verbal instructions, with Mini-mental State Examination ≥ 21;
- ability to participate in a therapy session lasting at least 30 minutes;
- consent to participant in the study
You may not qualify if:
- prior neurological or psychiatric disorders;
- severe spasticity (Modified Ashworth Scale \>3) over paretic arm;
- history of recent Botox injection or acupuncture to the paretic arm within the past three months;
- participation in another clinical study elsewhere apart from the study site during recruitment
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- The Hong Kong Polytechnic Universitylead
- Tung Wah Hospitalcollaborator
- Guangdong 999 Brain Hospitalcollaborator
Related Publications (1)
Longley V, Hazelton C, Heal C, Pollock A, Woodward-Nutt K, Mitchell C, Pobric G, Vail A, Bowen A. Non-pharmacological interventions for spatial neglect or inattention following stroke and other non-progressive brain injury. Cochrane Database Syst Rev. 2021 Jul 1;7(7):CD003586. doi: 10.1002/14651858.CD003586.pub4.
PMID: 34196963DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 21, 2019
First Posted
February 26, 2019
Study Start
July 1, 2016
Primary Completion
September 30, 2017
Study Completion
June 30, 2018
Last Updated
February 26, 2019
Record last verified: 2019-02
Data Sharing
- IPD Sharing
- Will not share