Comparison Between Uterine Artery Doppler and Placental Vascular Indices in Prediction of Preeclampsia

NCT03838887 | Unknown

• 1 other identifier: placental vascular indices
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

• Preeclampsia is a multisystem disorder that can cause considerable maternal and fetal morbidity and mortality. Late preeclampsia (with delivery \>34 weeks) is more frequent and less serious than early preeclampsia (with delivery \<34 weeks). Poor early placentation has been especially associated with early disease. Early identification of women at risk of preeclampsia is currently a crucial aim of antenatal care since they may benefit from prophylactic treatment and increased surveillance.

Conditions

Pre-Eclampsia

Outcome Measures

Primary Outcomes (1)

• placental vascular indices in prediction of preeclampsia

  placental vascular indices in prediction of preeclampsia compared to uterine artery doppler in prediction of preeclampsia

  one year

Study Arms (2)

control group

Pregnant women: 1. Age between 18-35 years 2. Parity: primigravidas and multiparas. 3. Have no history of preeclampsia or eclampsia. 4. Have no history of chronic hypertension. 5. Not diabetic. 6. Not have antiphospholipid syndrome. 7. Not have autoimmune disease such as SLE

Device: ultrasound machine

High risk group

Pregnant women with: 1. History of preeclampsia -Eclapmsia 2. Chronic hypertension 3. Diabetic 4. Antiphospholipid syndrome. 5. Autoimmune syndrome such as SLE.

Device: ultrasound machine

Interventions

ultrasound machine DEVICE

Ultrasound machine with a vocal software

High risk group; control group

Eligibility Criteria

• Age: 18 Years - 35 Years
• Gender Eligibility Details: examination of pregnant women
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

All pregnant women will be examined for antenatal care in the outpatient clinic and fetal medicine unit of obstetrics and gynecology department then they will be divided into two groups control and high risk

You may qualify if:

• A. Control group: Pregnant women:
• Age between 18-35 years
• Parity: primigravidas and multiparas.
• Have no history of preeclampsia or eclampsia.
• Have no history of chronic hypertension.
• Not diabetic.
• Not have antiphospholipid syndrome.
• Not have autoimmune disease such as SLE.
• B. High risk group: Pregnant women with:
• History of preeclampsia -Eclapmsia
• Chronic hypertension
• Diabetic
• Antiphospholipid syndrome.
• Autoimmune syndrome such as SLE.

You may not qualify if:

• Smoking
• Dichorionic placentae
• Fetal anomaly
• Uterine fibroid at the site of placental implantation
• Subchorionic hematoma

Sponsors & Collaborators

• National Research Centre, Egypt: lead

Study Sites (1)

National Research Centre

Cairo, 1234, Egypt

RECRUITING

MeSH Terms

Conditions

Pre-Eclampsia

Condition Hierarchy (Ancestors)

Hypertension, Pregnancy-Induced; Pregnancy Complications; Female Urogenital Diseases and Pregnancy Complications; Urogenital Diseases

Central Study Contacts

SHERIF MOHAMMED ELSIRGANY, DOCTOR

CONTACT

+201223607191; SHERIFELSIRGANY@YAHOO.COM

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Researcher ,Family Planning and Reproductive Health Department

Study Record Dates

• First Submitted: February 3, 2019
• First Posted: February 12, 2019
• Study Start: June 1, 2021
• Primary Completion: December 1, 2021
• Study Completion: January 1, 2022
• Last Updated: August 18, 2021

Record last verified: 2021-08

Locations

EG (1)