A Study of Neurofeedback for the Treatment of Parkinson's Disease
A Phase 1 Double-Blind Crossover Comparative Study of Neurofeedback for the Treatment of Parkinson's Disease
2 other identifiers
interventional
20
1 country
1
Brief Summary
This study aims to reveal relationship between brain activities and the symptoms of Parkinson disease when a neurofeedback training was applied for them.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable parkinson-disease
Started Jun 2019
Typical duration for not_applicable parkinson-disease
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 15, 2019
CompletedFirst Posted
Study publicly available on registry
February 12, 2019
CompletedStudy Start
First participant enrolled
June 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
March 31, 2022
CompletedSeptember 11, 2019
August 1, 2019
2.8 years
January 15, 2019
September 10, 2019
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Alteration of Brain Activities
measured by magnetoencephalography
At the time Immediately following the training
Secondary Outcomes (1)
The raw score change from baseline in the Movement disorder society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) part Ⅲ scores
At the time Immediately following the training
Study Arms (2)
Training with Neurofeedback
EXPERIMENTALThe other Training with Neurofeedback
EXPERIMENTALInterventions
Neurofeedback the brain activities by Magnetoencephalography
Neurofeedback the brain activities by Magnetoencephalography
Eligibility Criteria
You may qualify if:
- Subjects with age more than 20
- Subjects obtained the consent
- Subjects with Parkinson disease and healthy subjects
You may not qualify if:
- The subjects who can not conduct the tasks
- Subjects with severe illness
- Subjects whom the experimenter think as in appropriate
- Subjects with implantable devices such as pacemaker
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Osaka University
Suita, Osaka, 5650871, Japan
Related Publications (1)
Izutsu N, Yanagisawa T, Fukuma R, Kishima H. Magnetoencephalographic neurofeedback training decreasesbeta-low-gammaphase-amplitude coupling of the motor cortex of healthy adults: a double-blinded randomized crossover feasibility study. J Neural Eng. 2023 May 9;20(3). doi: 10.1088/1741-2552/acd0d6.
PMID: 37105162DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
January 15, 2019
First Posted
February 12, 2019
Study Start
June 1, 2019
Primary Completion
March 31, 2022
Study Completion
March 31, 2022
Last Updated
September 11, 2019
Record last verified: 2019-08
Data Sharing
- IPD Sharing
- Will not share