NCT03459586

Brief Summary

The purpose of this study is to determine if the 9zest app for Parkinson's disease is feasible, safe, and efficacious when used independently by individuals with Parkinson's disease.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
300

participants targeted

Target at P75+ for not_applicable parkinson-disease

Timeline
Completed

Started Feb 2018

Shorter than P25 for not_applicable parkinson-disease

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 24, 2018

Completed
4 days until next milestone

Study Start

First participant enrolled

February 28, 2018

Completed
9 days until next milestone

First Posted

Study publicly available on registry

March 9, 2018

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2018

Completed
Last Updated

March 9, 2018

Status Verified

March 1, 2018

Enrollment Period

9 months

First QC Date

February 24, 2018

Last Update Submit

March 2, 2018

Conditions

Keywords

Parkinson

Outcome Measures

Primary Outcomes (2)

  • Incidence of adverse events and falls during exercise using the 9 zest app

    At the end of the trial, the investigators will analyze the incidence of exercise-related adverse events and falls that occurred while exercising using the 9 zest app over the course of the study. These adverse events will be self-reported using a questionnaire and will be analyzed using frequencies, means, and measures of variability.

    12 week measurement point

  • Self-report questionnaire on the feasibility and usability of exercising using the 9 zest app

    A 5 point Likert style, self-report questionnaire with 6 items taken from the Intrinsic Motivation Inventory will be used to examine ease of use, design, user friendliness of exercising while using the 9zest app. Each of the 6 items will be reported separately. Scores range from 1 to 5 for each item.

    12 week measurement point

Secondary Outcomes (3)

  • The change in the number of times a participant can go from sitting to standing in 30 seconds

    Change in score from pretest to 3 posttests (4 week, 8 week, and 12 week measurement points)

  • The change in the amount of time a person can go from a sitting position to walking 3 meters, turning around and going back to sitting.

    Change in score from pretest to 3 posttests (4 week, 8 week, and 12 week measurement points)

  • The change in score on a self-report questionnaire of quality of life regarding mobility

    Change in score from pretest to 3 posttests (4 week, 8 week, and 12 week measurement points)

Study Arms (1)

9zest app facilitated exercise

EXPERIMENTAL

App to facilitate exercises for 3 times a week for 12 weeks. The app includes physical therapist-designed exercises that are modified using an algorithm to the participants physical capabilities and PD status. Exercises include strengthening, balance, range of motion, and endurance type exercise.

Other: 9zest app facilitated exercise

Interventions

The purpose of this study is to determine if the 9zest app for Parkinson's disease is feasible, safe, and efficacious when used independently by individuals with Parkinson's disease

9zest app facilitated exercise

Eligibility Criteria

Age40 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • English speaking men and women between 40 and 75 years old
  • Neurologist-diagnosed PD
  • A caregiver who is willing to assist the participant
  • Willingness to participate is a 12 week study
  • Be able to stand unassisted for 10 minutes
  • Stable on PD medication and deep brain stimulation for 3 months prior to trial

You may not qualify if:

  • Failure on a cognition screen
  • Co-morbidities that would preclude exercise participation or increase participant risk: severe osteoarthritis/pain, stroke, severe respiratory problems, traumatic brain injury, neuromuscular disease, atrial fibrillation, poorly controlled cardiovascular disease, limb amputation, osteoporosis)
  • Vision or hearing impairment that would interfere with app use
  • Fall that required physician evaluation (ED, urgent care, hospitalization) with the past year
  • Use of an assistive device (or person) for walking, standing, balance.
  • Currently use of a structured exercise regimen defined as participation in a regular exercise program consisting of more than 60 minutes per week in total

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Merrill Landers

Las Vegas, Nevada, 89154, United States

RECRUITING

Related Publications (1)

  • Landers MR, Ellis TD. A Mobile App Specifically Designed to Facilitate Exercise in Parkinson Disease: Single-Cohort Pilot Study on Feasibility, Safety, and Signal of Efficacy. JMIR Mhealth Uhealth. 2020 Oct 5;8(10):e18985. doi: 10.2196/18985.

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Study Officials

  • Merrill Landers, DPT, PhD

    UNLV, Las Vegas

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sam Majmundar, MS

CONTACT

Merrill Landers, DPT, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Model Details: The purpose of this study is to determine if the 9zest app for Parkinson's disease is feasible, safe, and efficacious when used independently by individuals with Parkinson's disease.
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 24, 2018

First Posted

March 9, 2018

Study Start

February 28, 2018

Primary Completion

December 1, 2018

Study Completion

December 1, 2018

Last Updated

March 9, 2018

Record last verified: 2018-03

Data Sharing

IPD Sharing
Will not share

Locations