NCT03834207

Brief Summary

To assess the acceptability of a personalised ICT tool that facilitates coordinated care planning, treatment optimisation and patient self-management for patients with multiple long term conditions and their team of health professionals.

Trial Health

47
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
672

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Oct 2018

Geographic Reach
3 countries

3 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2018

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

January 2, 2019

Completed
1 month until next milestone

First Posted

Study publicly available on registry

February 7, 2019

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2020

Completed
Last Updated

February 7, 2019

Status Verified

February 1, 2019

Enrollment Period

1.3 years

First QC Date

January 2, 2019

Last Update Submit

February 5, 2019

Conditions

Keywords

C3-CloudMultimorbidityDiabetes Type 2Heart FailureCardiac FailureDepressionRenal FailureKidney FailureAgeingComputer SystemInformation TechnologyPatient EmpowermentGuideline ReconciliationPolypharmacyIntegrated CareClinical Decision Support

Outcome Measures

Primary Outcomes (1)

  • Acceptability & usefulness of the C3-Cloud system

    This is qualitative research so the primary outcome measure will be the acceptability and usefulness of the technology by patients, informal care givers and health \& care professionals. The UTAUT questionnaire (Unified Theory of Acceptance and User of Technology) will be performed to determine C3-Cloud user responses along the following UTAUT categories: performance expectancy, effort expectancy, social influence, cultural and language factors, technology anxiety, adoption timeline and associated facilitating conditions on the intended adoption behaviour. The questionnaire will be performed online and data will be aggregated completely anonymously using the online questionnaire platform "LimeSurvey", hosted on servers of empirica. The ordinal responses (e.g. "I strongly disagree" or "I strongly agree") are clustered along the UTAUT categories analsed anonymously.

    12 months

Study Arms (1)

Intervention Group

EXPERIMENTAL

Use of the C3-Cloud IT system

Device: Use of the C3-Cloud IT system

Interventions

Patients who are recruited to the intervention arm will use the C3-Cloud system during the pilot study.

Intervention Group

Eligibility Criteria

Age55 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • They are aged 55 or older
  • They are multimorbid patients that suffer from two or more of the following four conditions in various disease combinations (two conditions set as the minimum threshold):-
  • Diabetes type 2
  • Renal Failure with eGFR/GFR 30 - 59 (measured or estimated glomerular filtration rate)
  • Heart Failure in compliance with NYHA I-II (New York Heart Association classification of heart failure)
  • Mild or moderate depression
  • They still live and generally plan on living in their home (or in the community) for the 12-month trial duration.
  • They or their informal caregiver pass the ICT Handling Self-Check (see Deliverable D10.4, Annex 8.3) (i.e. they have access to and some familiarity with the use of ICT).
  • They, or their informal caregiver, have stable access to the internet and at least one of the following devices readily available to use the C3-Cloud components: Computer; Notebook; Smartphone; Tablet. This includes the use of Internet Browsers to open the C3-Cloud patient dashboards online.
  • They are able to provide informed consent.

You may not qualify if:

  • They are aged 54 or below
  • They suffer from any of the following conditions:
  • Severe Renal Failure with eGFR/GFR \<30
  • Severe Heart Failure in compliance with NYHA III-IV
  • Severe depression
  • They have other debilitating conditions that impair their decision making capability or their life expectancy (e.g. end-of-life patients or cancer patients)
  • They or their informal caregivers do not pass the ICT Handling Self-Check (i.e. they do not have access to suitable IT devices and do not have some familiarity with the use of ICT).
  • They have disabilities or other health conditions that would prevent their active involvement in the study project or which prevent them from carrying out essential functions of the trial.
  • They live in a care institution, for instance in a residential home or nursing home.
  • Their health care expenses are covered by a private insurance: in the C3-Cloud pilot sites, private insurances have no data exchange with EHRs.
  • They do not speak the regional language: English for SWFT; Spanish for the Basque country; Swedish for RJH
  • They are unable to provide informed consent for study participation.
  • Patients with further chronic diseases and other co-morbidities or symptoms, for example, frailty, sleeping problems, malnourishment or anxiety, will not be excluded from recruitment. Informal caregivers who pass the ICT Handling Self-Check can substitute for the patient if the patient does not pass the ICT Handling Self-Check - the patient-informal caregiver pair can then still be recruited.
  • They are aged 17 or below
  • They do not have some familiarity with the use of ICT or do not have the capability to help the patient out with ICT usage if necessary.
  • +8 more criteria

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Osakidetza

Vitoria-Gasteiz, Araba, 01006, Spain

NOT YET RECRUITING

Region Jamtland Harjedalen

Östersund, S-831 27, Sweden

RECRUITING

South Warwickshire NHS Foundation Trust

Warwick, Warwickshire, CV34 5BW, United Kingdom

NOT YET RECRUITING

Related Publications (1)

  • von Tottleben M, Grinyer K, Arfa A, Traore L, Verdoy D, Lim Choi Keung SN, Larranaga I, Jaulent MC, De Manuel Keenoy E, Lilja M, Beach M, Marguerie C, Yuksel M, Laleci Erturkmen GB, Klein GO, Lindman P, Mar J, Kalra D; C3-Cloud Research Team; Arvanitis TN. An Integrated Care Platform System (C3-Cloud) for Care Planning, Decision Support, and Empowerment of Patients With Multimorbidity: Protocol for a Technology Trial. JMIR Res Protoc. 2022 Jul 13;11(7):e21994. doi: 10.2196/21994.

Related Links

MeSH Terms

Conditions

Diabetes Mellitus, Type 2Renal InsufficiencyHeart FailureDepressionChronic DiseasePatient Participation

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesHeart DiseasesCardiovascular DiseasesBehavioral SymptomsBehaviorDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsPatient Acceptance of Health CareTreatment Adherence and ComplianceHealth Behavior

Study Officials

  • Theodoros N. Arvanitis

    University of Warwick

    STUDY CHAIR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Model Details: A single intervention group that will use and evaluate the C3-Cloud system during the 12 month study. Please note that an anonymous group of patients meeting the same criteria will be identified retrospectively at the end of the study so that healthcare resource utilisation during the same period can be compared.
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Consultant Rheumatologist/Associate Medical Director for Research

Study Record Dates

First Submitted

January 2, 2019

First Posted

February 7, 2019

Study Start

October 1, 2018

Primary Completion

January 31, 2020

Study Completion

April 30, 2020

Last Updated

February 7, 2019

Record last verified: 2019-02

Data Sharing

IPD Sharing
Will not share

Only anonymised, aggregated data will be shared with researchers.

Locations