NCT03828812

Brief Summary

The study includes two parts: 1) an observational study examines the association of meal frequency, meal timing, and meal regularity with short-term changes in blood pressure and body composition; 2) a randomized controlled intervention examines the influence of recommendation of increase breakfast frequency and decrease nighttime snacking on 1-year changes in blood pressure and body composition.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
125

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2015

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2015

Completed
3.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2018

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2018

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

January 30, 2019

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 4, 2019

Completed
Last Updated

June 25, 2020

Status Verified

June 1, 2020

Enrollment Period

3.3 years

First QC Date

January 30, 2019

Last Update Submit

June 23, 2020

Conditions

Outcome Measures

Primary Outcomes (6)

  • Body weight

    Body weight in kilogram

    1 year

  • Standing height

    Height in meters

    1 year

  • Body fat%

    Bioimpedance method (TANITA BC-418)

    1 year

  • Body mass index

    Weight and height will be combined to report BMI in kg/m\^2

    1 year

  • Systolic blood pressure

    Measured in mmHg (Microlife BP 3MS1-4K)

    1 year

  • Diastolic blood pressure

    Measured in mmHg (Microlife BP 3MS1-4K)

    1 year

Secondary Outcomes (2)

  • Frequency of breakfast per week

    1 year

  • Frequency of nighttime snacking per week

    1 year

Other Outcomes (2)

  • Sleep quality score

    1 year

  • Mood status

    1 year

Study Arms (3)

Breakfast promotion

ACTIVE COMPARATOR

Receiving the recommendation of daily breakfast

Behavioral: Breakfast promotion

Nighttime snack reduction

ACTIVE COMPARATOR

Receiving the recommendation of reducing nighttime snack frequency

Behavioral: Nighttime snack reduction

Breakfast promotion + nighttime snack reduction

EXPERIMENTAL

Receiving the recommendation of daily breakfast + reducing nighttime snack frequency

Behavioral: Breakfast promotionBehavioral: Nighttime snack reduction

Interventions

Recommendation of having breakfast daily

Breakfast promotionBreakfast promotion + nighttime snack reduction

Recommendation of reducing frequency of nighttime snacking

Breakfast promotion + nighttime snack reductionNighttime snack reduction

Eligibility Criteria

Age20 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult
  • Willing to participate

You may not qualify if:

  • Being pregnant
  • hemodialysis patients
  • clinical diagnosis of cardiovascular diseases
  • clinical diagnosis of cancer
  • clinical diagnosis of dementia
  • clinical diagnosis of eating disorders
  • having metal orthopedic implants
  • having pacemaker implanted

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Chen HJ, Tsai YC, Hsu YT, Chu J. Effect of recommendations of breakfast and late-evening snack habits on body composition and blood pressure: A pilot randomized trial. Chronobiol Int. 2024 Jul;41(7):1021-1033. doi: 10.1080/07420528.2024.2363492. Epub 2024 Jun 11.

Study Officials

  • Hsin-Jen Chen, PhD

    National Yang Ming Chiao Tung University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

January 30, 2019

First Posted

February 4, 2019

Study Start

August 1, 2015

Primary Completion

October 31, 2018

Study Completion

December 31, 2018

Last Updated

June 25, 2020

Record last verified: 2020-06