NCT03824340

Brief Summary

Infertility is a common gynecological problem is women

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2019

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 25, 2019

Completed
5 days until next milestone

Study Start

First participant enrolled

January 30, 2019

Completed
1 day until next milestone

First Posted

Study publicly available on registry

January 31, 2019

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2019

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2020

Completed
Last Updated

August 6, 2019

Status Verified

August 1, 2019

Enrollment Period

10 months

First QC Date

January 25, 2019

Last Update Submit

August 4, 2019

Conditions

Infertility

Outcome Measures

Primary Outcomes (1)

  • the number of women who will have successful ICSI

    The number of women who will get pregnant after ICSI with extra treatment

    within 4 months

Study Arms (2)

Doxycycline before ICSI

ACTIVE COMPARATOR

extra medications (Doxycycline ) group before ICSI : in which Women who will receive the Doxyxycline before ICSI Intervention : Women will receive Doxycycline before ICSI

Drug: Doxycycline before ICSI

control group

NO INTERVENTION

control group : No intervention : in which Women willnot receive the extra medications (Doxycycline ) before ICSI

Interventions

Doxycycline before ICSIDRUG

Extra medication (Doxycycline ) group before ICSI :,women who will receive more medications (Doxycycline ) before starting the ICSI process

Also known as: Medical treatment with Doxycycline
Doxycycline before ICSI

Eligibility Criteria

Age20 Years - 42 Years
Sexfemale(Gender-based eligibility)
Gender Eligibility Detailsinfertile women
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Women who have infertility with age between 20 -42 years

You may not qualify if:

  • women who has ovarian or endometrial factor of infertility

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Algazeerah

Giza, Egypt

RECRUITING

MeSH Terms

Conditions

Infertility

Interventions

Doxycycline

Condition Hierarchy (Ancestors)

Genital DiseasesUrogenital Diseases

Intervention Hierarchy (Ancestors)

TetracyclinesNaphthacenesPolycyclic Aromatic HydrocarbonsHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbonsOrganic ChemicalsPolycyclic Compounds

Study Officials

  • Mahmoud Alalfy, PhD

    Algazeerah hospital -Location (Giza -Egypt ) and National Research centre egypt

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mahmoud Alalfy, PhD

CONTACT

01002611058mahmoudalalfy@ymail.com

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, CARE PROVIDER
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: A randomized controlled study
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 25, 2019

First Posted

January 31, 2019

Study Start

January 30, 2019

Primary Completion

November 30, 2019

Study Completion

January 1, 2020

Last Updated

August 6, 2019

Record last verified: 2019-08

Locations

EG(1)