NCT03818555

Brief Summary

Postmarket study of Sebacia Microparticles treatment during adoption into clinical use for patients with mild to moderate inflammatory acne vulgaris.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
125

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2019

Typical duration for not_applicable

Geographic Reach
1 country

6 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2019

Completed
23 days until next milestone

First Submitted

Initial submission to the registry

January 24, 2019

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 28, 2019

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2021

Completed
Last Updated

October 27, 2020

Status Verified

October 1, 2020

Enrollment Period

2.4 years

First QC Date

January 24, 2019

Last Update Submit

October 24, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • Inflammatory Lesion Count

    Percent change in number of inflammatory lesions from baseline

    Months 2, 3, 6, 9 and 12

Secondary Outcomes (2)

  • Investigator's Global Assessment

    Months 2, 3, 6, 9 and 12

  • Physician's Overall Assessment of Improvement

    Months 2, 3, 6, 9 and 12

Study Arms (1)

Sebacia Microparticles Treatment

OTHER
Other: Sebacia Microparticles Treatment

Interventions

Sebacia Microparticles procedure involving microparticles and 1064 nm laser. Three treatment procedures over a two-week period.

Also known as: Sebacia treatment, Microparticles and Nd:Yag laser treatment
Sebacia Microparticles Treatment

Eligibility Criteria

Age12 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Mild to moderate facial inflammatory acne vulgaris (IGA 2 or 3)
  • Between 10 and 50 papules/pustules
  • Fitzpatrick skin phototype I, II or III
  • Able to provide informed consent and comply with study schedule and other requirements

You may not qualify if:

  • Moderately severe or severe acne vulgaris (IGA 4 or 5)
  • Nodulocystic acne, significant scarring or excoriation
  • Requires oral retinoid, antibiotic or corticosteroid for acne
  • New or fluctuating hormone or hormone-regulating therapy
  • Photosensitivity or allergy to gold
  • Medical or mental health condition that would pose a risk to patient or impair treatment and evaluation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (6)

Miami Dermatology & Laser Institute

Miami, Florida, 33173, United States

Location

Dermatology Institute of Boston

Boston, Massachusetts, 02116, United States

Location

International Clinical Research

Murfreesboro, Tennessee, 37130, United States

Location

Austin Institute for Clinical Research - Central

Austin, Texas, 78705, United States

Location

Austin Institute for Clinical Research - Pflugerville

Pflugerville, Texas, 78660, United States

Location

Premier Clinical Research

Spokane, Washington, 99202, United States

Location

Related Links

MeSH Terms

Conditions

Acne Vulgaris

Condition Hierarchy (Ancestors)

Acneiform EruptionsSkin DiseasesSkin and Connective Tissue DiseasesSebaceous Gland Diseases

Study Officials

  • VP, Clinical & Regulatory Affairs

    Sebacia, Inc.

    STUDY DIRECTOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 24, 2019

First Posted

January 28, 2019

Study Start

January 1, 2019

Primary Completion

June 1, 2021

Study Completion

June 1, 2021

Last Updated

October 27, 2020

Record last verified: 2020-10

Data Sharing

IPD Sharing
Will not share

Locations