NCT03303170

Brief Summary

Prospective, randomized, controlled, parallel group clinical study with blinded assessment evaluating Sebacia Microparticles (SM) with Nd:Yag laser in facial inflammatory acne vulgaris

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
168

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Sep 2017

Shorter than P25 for not_applicable

Geographic Reach
1 country

11 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 25, 2017

Completed
7 days until next milestone

First Submitted

Initial submission to the registry

October 2, 2017

Completed
3 days until next milestone

First Posted

Study publicly available on registry

October 5, 2017

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 10, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

April 10, 2018

Completed
Last Updated

October 14, 2019

Status Verified

October 1, 2019

Enrollment Period

7 months

First QC Date

October 2, 2017

Last Update Submit

October 2, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change in number of inflammatory acne lesions

    Week 12

Study Arms (2)

Sebacia Microparticles

EXPERIMENTAL
Device: Sebacia Microparticles

Nd:Yag Laser

ACTIVE COMPARATOR
Device: Nd:Yag Laser

Interventions

Topical microparticle suspension

Sebacia Microparticles

Laser delivering 1064 nm wavelength light

Nd:Yag Laser

Eligibility Criteria

Age12 Years - 45 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Mild to moderate acne vulgaris
  • At least 15 inflammatory acne lesions
  • Skin phototype I - III
  • Able to understand and comply with study requirements

You may not qualify if:

  • Severe acne vulgaris
  • Nodulocystic acne
  • Ongoing use of medications and/or treatments for acne
  • New hormone regimen (used for less than 12 weeks)
  • Significant medical or mental health condition

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (11)

Clear Dermatology & Aesthetics Center

Scottsdale, Arizona, 85255, United States

Location

Scripps Health

San Diego, California, 92121, United States

Location

Miami Dermatology & Laser Institute

Miami, Florida, 33173, United States

Location

Meridian Clinical Research

Savannah, Georgia, 31406, United States

Location

MediSearch Clinical Trials

Saint Joseph, Missouri, 64506, United States

Location

Dermatology, Laser & Vein Institute

Charlotte, North Carolina, 28207, United States

Location

Wake Research Associates

Raleigh, North Carolina, 27612, United States

Location

International Clinical Research

Murfreesboro, Tennessee, 37130, United States

Location

Austin Institute for Clinical Research

Austin, Texas, 78660, United States

Location

The Center for Skin Research

Katy, Texas, 77494, United States

Location

Premier Clinical Research

Spokane, Washington, 99202, United States

Location

Related Links

MeSH Terms

Conditions

Acne Vulgaris

Condition Hierarchy (Ancestors)

Acneiform EruptionsSkin DiseasesSkin and Connective Tissue DiseasesSebaceous Gland Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 2, 2017

First Posted

October 5, 2017

Study Start

September 25, 2017

Primary Completion

April 10, 2018

Study Completion

April 10, 2018

Last Updated

October 14, 2019

Record last verified: 2019-10

Locations