ReNEW Clinic Cohort Study

NCT03816462 | Completed DMC

• 1 other identifier: IRB00056175
• Study Type: observational
• Target: 200
• Locations: 1 country
• Sites: 1

Brief Summary

This is an ongoing, prospective cohort study of children and young adults who are evaluated in the Reversing the Negative Effects of Weight on the Heart (ReNEW) Clinic at Johns Hopkins University. Demographic and clinical data of patients who agree to participate are obtained via chart review and entered into a longitudinal clinic registry.

Conditions

Hypertension; Prehypertension; Obesity; Overweight; Left Ventricular Hypertrophy; Elevated Blood Pressure

Outcome Measures

Primary Outcomes (1)

• Demographic and clinical data obtained via chart review

  This is a clinic based registry of cardiovascular disease risk data from participants to be collected over time.

  20 years

Eligibility Criteria

• Age: Up to 22 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Children between birth and 22 years of age with overweight or obesity referred for evaluation of elevated blood pressure in the ReNEW Clinic at Johns Hopkins University

You may qualify if:

• Children and young adults with overweight or obesity referred for evaluation of elevated blood pressure in the ReNEW Clinic at Johns Hopkins University are eligible.

You may not qualify if:

• Children who are wards of the state or who are non-English speaking without an in-person interpreter accompanying them to the clinic visit.

Sponsors & Collaborators

• Johns Hopkins University: lead
• National Institutes of Health (NIH): collaborator

Study Sites (1)

Johns Hopkins University

Baltimore, Maryland, 21287, United States

Location

Related Publications (2)

• Wen W, Psoter KJ, Solomon BS, Urbina EM, Brady TM. Accuracy and Performance of Triage Blood Pressure Measurements in A Real-World Clinic Setting. J Pediatr. 2024 Jun;269:113962. doi: 10.1016/j.jpeds.2024.113962. Epub 2024 Feb 17.

  PMID: 38369238 DERIVED

• Ducharme-Smith K, Brady TM, Vizthum D, Caulfield LE, Mueller NT, Rosenstock S, Garcia-Larsen V. Diet quality scores associated with improved cardiometabolic measures among African American adolescents. Pediatr Res. 2022 Sep;92(3):853-861. doi: 10.1038/s41390-021-01893-w. Epub 2021 Dec 16.

  PMID: 34916627 DERIVED

Related Links

• Please visit the above link for more information. To make an appointment at the ReNEW Clinic, please call 410-955-1247.

MeSH Terms

Conditions

Hypertension; Prehypertension; Obesity; Overweight; Hypertrophy, Left Ventricular

Condition Hierarchy (Ancestors)

Vascular Diseases; Cardiovascular Diseases; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Cardiomegaly; Heart Diseases; Hypertrophy; Pathological Conditions, Anatomical

Study Officials

• Tammy M Brady

  Johns Hopkins University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 22, 2019
• First Posted: January 25, 2019
• Study Start: January 1, 2015
• Primary Completion: January 1, 2026
• Study Completion: January 1, 2026
• Last Updated: January 20, 2026

Record last verified: 2026-01

Locations

US (1)