The Effect of Radiofrequency Ablation of Genicular Nerves on Postural Stability in Patients With Knee Osteoarthritis

NCT03816124 | Unknown

• 1 other identifier: 09.2018.663
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

In advanced knee osteoarthritis, postural stability is also disturbed. There are some concerns about performing radiofrequency ablation to genicular nerves since this may further decrease the postural stability of the patient. The aim of this study is to see if application of genicular radiofrequency causes a significant change in postural stability.

Conditions

Osteoarthritis, Knee

Keywords

osteoarthritis; radiofrequency ablation

Outcome Measures

Primary Outcomes (1)

• Visual analogue scale

  The change of pain will be evaluated with 10 cm visual analogue scale will be applied to the patients, 0 being no pain while 10 being intolerable pain

  3 weeks and 3 months after the intervention

Secondary Outcomes (2)

• Postural stability

  3 weeks and 3 months after the treatment

• WOMAC

  3 weeks and 3 months after the treatment

Study Arms (1)

Genicular RF

EXPERIMENTAL

Patients who will receive genicular radiofrequency ablation

Procedure: radiofrequency ablation

Interventions

radiofrequency ablation PROCEDURE

radiofrequency ablation of the genicular nerves

Genicular RF

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Stage 3 and 4 knee osteoarthritis according to Kellgren-Lawrance scale
• Knee pain more than 3 months

You may not qualify if:

• Neurological diseases such as polyneuropathies
• Presence of severe psychiatric disorders
• Hemodynamic instability
• History of any surgery from the knee

Sponsors & Collaborators

• Marmara University: lead

Study Sites (1)

Marmara University School of Medicine Department of Physical Medicine and Rehabilitation

Istanbul, 34899, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Osteoarthritis, Knee; Osteoarthritis

Interventions

Radiofrequency Ablation

Condition Hierarchy (Ancestors)

Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases

Intervention Hierarchy (Ancestors)

Radiofrequency Therapy; Therapeutics; Ablation Techniques; Surgical Procedures, Operative

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: Patients with knee osteoarthritis with Kellgren-Lawrance scale stage 3-4 will receive radiofrequency ablation to their genicular nerves and will be evaluated before treatment, 3 weeks and 3 months after treatment.

Study Record Dates

• First Submitted: December 3, 2018
• First Posted: January 25, 2019
• Study Start: December 1, 2018
• Primary Completion: June 1, 2019
• Study Completion: December 1, 2019
• Last Updated: January 25, 2019

Record last verified: 2019-01

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)