Comprehensive Assessment of Subclinical Atherosclerosis in Patients With Rheumatoid Arthritis
1 other identifier
observational
100
0 countries
N/A
Brief Summary
Cardiovascular disease is a leading cause for morbidity and mortality in general population. The incidence of cardiovascular disease and their poor outcome is well documented in a broad spectrum of connective tissue diseases, especially in rheumatoid arthritis (RA). The risk of incident CVD is increased by 48% in patients with RA compared to the general population. RA is associated with 50% increase in the mortality in patients with cardiovascular disease (CVD). One reason is the more frequent cardiovascular risk factors in RA patients compared with the general population. Patients with RA have a high risk of premature cardiovascular disease (CVD). The aim of the present study is to assess whether there are non-invasive measures that might predict arteriosclerosis in RA patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Oct 2019
Shorter than P25 for all trials
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 13, 2019
CompletedFirst Posted
Study publicly available on registry
January 23, 2019
CompletedStudy Start
First participant enrolled
October 1, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2020
CompletedJuly 10, 2019
July 1, 2019
5 months
January 13, 2019
July 9, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Cardiovascular disease risks in patient with theumatoid arthritis
Prediction of cardiovascular risks and proposed preventive treatment
6 months
Eligibility Criteria
This study will be conducted in Ziv Medical Center, Safed, Internal Medicine Department A, on 100 patients with rheumatoid artheritis
You may qualify if:
- years old (except for women till 75 years old)
- Absence of established CVD:
- Myocardial Infarction p/h
- PCI with balloon and/or stent
- Intermittent claudication
- PAD / intervention
- CAS /intervention
- Signed informed consent form
- Documented diagnosis of rheumatoid arthritis
You may not qualify if:
- Known CVD
- Pregnancy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Ziv Hospitallead
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 6 Months
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Head of Internal Medicine A
Study Record Dates
First Submitted
January 13, 2019
First Posted
January 23, 2019
Study Start
October 1, 2019
Primary Completion
March 1, 2020
Study Completion
July 1, 2020
Last Updated
July 10, 2019
Record last verified: 2019-07