NCT03807713

Brief Summary

The objective of the study is to compare the outcomes after a surgical procedure with minimally invasive Ponto surgery (MIPS, test group) and tissue preservation surgery (control) for placing Oticon Medical Ponto implants and abutments.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
25

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 7, 2018

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

January 8, 2019

Completed
9 days until next milestone

First Posted

Study publicly available on registry

January 17, 2019

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 6, 2019

Completed
2.4 years until next milestone

Study Completion

Last participant's last visit for all outcomes

March 29, 2022

Completed
Last Updated

April 20, 2022

Status Verified

March 1, 2021

Enrollment Period

1.2 years

First QC Date

January 8, 2019

Last Update Submit

April 19, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Numbness (sensibility) around the implant

    Total numbness around the implant will be assessed as a combination of gnostic and vital sensibility.

    6 months post surgery

Secondary Outcomes (14)

  • Length of surgery

    At surgery

  • Unplanned visits

    36 months

  • Adverse skin reactions

    36 months

  • Adverse skin reactions

    36 months

  • Pain perception by patient

    36 months

  • +9 more secondary outcomes

Study Arms (1)

Minimally Invasive Ponto Surgery

OTHER

Surgical method for installation of a bone anchored hearing system for hearing rehabilitation

Device: Minimally Invasive Ponto Surgery

Interventions

Minimally Invasive Ponto surgery is used for hearing rehabilitation using Ponto Wide Implants in patients indicated and counselled for Bone Anchored Hearing Systems.

Minimally Invasive Ponto Surgery

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • years or older.
  • Patient indicated for an ear level bone anchored sound processor.
  • Healthy bone quality to allow for 4mm implant insertion.

You may not qualify if:

  • Intraoperative switch to an alternative surgical technique
  • Patients undergoing re-implantation (on the side being included in the study)
  • Previous participation in the C47 study.
  • Inability to participate in follow-up.
  • Psychiatric disease in the medical history.
  • Mental disability.
  • Presumed doubt, for any reason, that the patient will be able to show up on all follow-ups.
  • Diseases or treatments known to compromise the bone quality at the implant site, e.g. radiotherapy, osteoporosis, diabetes mellitus.
  • Patients with natural skin height of \>12mm (as there will be additional skin reduction needed)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Radboud University Medical Center

Nijmegen, 6525, Netherlands

Location

MeSH Terms

Conditions

Hearing Loss, UnilateralHearing Loss, Mixed Conductive-Sensorineural

Condition Hierarchy (Ancestors)

Hearing LossHearing DisordersEar DiseasesOtorhinolaryngologic DiseasesSensation DisordersNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Myrthe Hol, MD, PhD

    Radboud UMC, Department of Otorhinolaryngology. The Netherlands

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 8, 2019

First Posted

January 17, 2019

Study Start

September 7, 2018

Primary Completion

November 6, 2019

Study Completion

March 29, 2022

Last Updated

April 20, 2022

Record last verified: 2021-03

Data Sharing

IPD Sharing
Will not share

Locations