Hyaluronic Acid With Scaling & Root Planing In Chronic Periodontitis Patients With Diabetes Mellitus Type 2
Adjunctive Use Of Hyaluronic Acid With Scaling & Root Planing In Treatment of Chronic Periodontitis Patients With Diabetes Mellitus Type 2: A Randomized Controlled Trial
1 other identifier
interventional
30
1 country
1
Brief Summary
The present study aimed to assess the adjunctive use of Hyaluronic acid with scaling \& root planing (SRP) in patients with chronic periodontitis \& diabetes mellitus type 2.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Mar 2017
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
March 16, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 29, 2017
CompletedStudy Completion
Last participant's last visit for all outcomes
June 29, 2017
CompletedFirst Submitted
Initial submission to the registry
January 15, 2019
CompletedFirst Posted
Study publicly available on registry
January 17, 2019
CompletedJanuary 18, 2019
January 1, 2019
4 months
January 15, 2019
January 16, 2019
Conditions
Outcome Measures
Primary Outcomes (1)
Gain in clinical attachment level
Gain in clinical attachment level will be measured in millimeter by William's graduated periodontal probe
12 weeks
Study Arms (2)
SRP group
ACTIVE COMPARATORChronic periodontitis patients with type 2 diabetes mellitus recieved Periodontal treatment in the form of scaling \& root planing (SRP) alone.
Hyaluronic acid & SRP group
EXPERIMENTALChronic periodontitis \& type 2 diabetes mellitus patients received Periodontal treatment in the form of scaling \& root planing (SRP) with the adjunctive use of hyaluronic acid.
Interventions
In addition to SRP, patients in the test group received adjunct subgingival application of hyaluronic acid in all selected periodontal pockets.
Patients received full-mouth supra- \& sub-gingival SRP with the use of ultrasonic device \& periodontal universal \& Gracey curettes under local anesthesia.
Eligibility Criteria
You may qualify if:
- Patients with chronic periodontitis and type 2 diabetes mellitus
- Minimum of 20 teeth
- Clinical attachment level (CAL) ≥ 3 mm
- Probing depth (PD) ≥ 4 mm.
You may not qualify if:
- Pregnant females
- Smokers
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Faculty of Dentistry, Cairo University
Cairo, 12411, Egypt
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Gihane G Madkour, Ass Prof
Cairo University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
January 15, 2019
First Posted
January 17, 2019
Study Start
March 16, 2017
Primary Completion
June 29, 2017
Study Completion
June 29, 2017
Last Updated
January 18, 2019
Record last verified: 2019-01
Data Sharing
- IPD Sharing
- Will not share