NCT03766360

Brief Summary

The current study proposes an open clinical trial to investigate the effectiveness of a social functioning intervention on bariatric surgery outcomes and depression. The treatment will be administered in a group format over 10 weekly/biweekly sessions and will take place at the University of Washington Weight Loss Management Clinic (WLMC) at the Roosevelt Clinic location. Effects of the intervention will be measured with self-report questionnaires and by self-report of behaviors outside of assessment sessions (via questionnaires and self-report of adherence to treatment). Data collection will occur at specific time points including before treatment, after treatment, and two months after treatment.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable depression

Timeline
Completed

Started Jan 2019

Shorter than P25 for not_applicable depression

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 27, 2018

Completed
9 days until next milestone

First Posted

Study publicly available on registry

December 6, 2018

Completed
26 days until next milestone

Study Start

First participant enrolled

January 1, 2019

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2019

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2019

Completed
Last Updated

December 6, 2018

Status Verified

December 1, 2018

Enrollment Period

5 months

First QC Date

November 27, 2018

Last Update Submit

December 4, 2018

Conditions

Outcome Measures

Primary Outcomes (3)

  • Patient Health Questionnaire-9 (PHQ-9)

    based directly on the nine diagnostic criteria for major depressive disorder in the Diagnostic and Statistical Manual Diploma in Social Medicine-IV

    Baseline

  • Patient Health Questionnaire-9 (PHQ-9)

    based directly on the nine diagnostic criteria for major depressive disorder in the Diagnostic and Statistical Manual Diploma in Social Medicine-IV

    Post Intervention (Approximately 12 Weeks from Baseline)

  • Patient Health Questionnaire-9 (PHQ-9)

    based directly on the nine diagnostic criteria for major depressive disorder in the Diagnostic and Statistical Manual Diploma in Social Medicine-IV

    Follow Up (3 Months after Intervention)

Secondary Outcomes (24)

  • World Health Organization Quality of Life

    Baseline

  • World Health Organization Quality of Life

    Post Intervention (Approximately 12 Weeks from Baseline)

  • World Health Organization Quality of Life

    Follow Up (3 Months after Intervention)

  • Drug Abuse Screening Test

    Baseline

  • Drug Abuse Screening Test

    Post Intervention (Approximately 12 Weeks from Baseline)

  • +19 more secondary outcomes

Study Arms (2)

FAP Intervention Group

EXPERIMENTAL

All of the clients in the FAP intervention group will begin treatment at the same time and complete 3 assessments.

Behavioral: Functional Analytical Psychotherapy (FAP)

Control Group

NO INTERVENTION

The clients in the control group will take their assessments at the same time as those in the FAP intervention group.

Interventions

The intervention itself is based on the procedures of Functional Analytic Psychotherapy, a behavioral intervention focusing on improving social functioning.

FAP Intervention Group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Older than 18
  • Speak English as a primary language
  • Had Bariatric Surgery in the past 6-24 months (bypasses (Roux-en-Y) or sleeves)
  • Yes to one or both of the first two PHQ-9 Questions
  • Not pregnant
  • Not traveling anywhere in the next 6 months
  • No surgeries scheduled in the next 12 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Weight Loss Management Center at UWMC-Roosevelt

Seattle, Washington, 98105, United States

Location

Related Publications (5)

  • Buchwald H, Estok R, Fahrbach K, Banel D, Jensen MD, Pories WJ, Bantle JP, Sledge I. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med. 2009 Mar;122(3):248-256.e5. doi: 10.1016/j.amjmed.2008.09.041.

    PMID: 19272486BACKGROUND
  • Switzer, N.J., Debru, E., Church, N. et al. Curr Cardiovasc Risk Rep (2016) 10: 12. https://doi.org/10.1007/s12170-016-0492-7

    BACKGROUND
  • Mitchell JE, Crosby R, de Zwaan M, Engel S, Roerig J, Steffen K, Gordon KH, Karr T, Lavender J, Wonderlich S. Possible risk factors for increased suicide following bariatric surgery. Obesity (Silver Spring). 2013 Apr;21(4):665-72. doi: 10.1002/oby.20066.

    PMID: 23404774BACKGROUND
  • Sarwer DB, Moore RH, Spitzer JC, Wadden TA, Raper SE, Williams NN. A pilot study investigating the efficacy of postoperative dietary counseling to improve outcomes after bariatric surgery. Surg Obes Relat Dis. 2012 Sep-Oct;8(5):561-8. doi: 10.1016/j.soard.2012.02.010. Epub 2012 Mar 21.

    PMID: 22551576BACKGROUND
  • Kohlenberg, R. J., & Tsai, M. (1991). Functional analytic psychotherapy: Creating intense and curative therapeutic relationships. New York, NY, US: Plenum Press. http://dx.doi.org/10.1007/978-0-387-70855-3

    BACKGROUND

MeSH Terms

Conditions

Depression

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehavior

Central Study Contacts

Jonathan Kanter, PhD

CONTACT

Elliot Wallace

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor

Study Record Dates

First Submitted

November 27, 2018

First Posted

December 6, 2018

Study Start

January 1, 2019

Primary Completion

June 1, 2019

Study Completion

December 1, 2019

Last Updated

December 6, 2018

Record last verified: 2018-12

Locations