Outcome After Out of Hospital Cardiac Arrest in Bern, Switzerland
1 other identifier
observational
1,000
1 country
1
Brief Summary
Sudden cardiac arrests is one of the most frequent causes of death. In Switzerland every year 8000-10.000 people suffer from a cardiac arrest. The EuReCa ONE Study showed regional differences in incidence and chances of survival after cardiac arrests in Europe. The current European Resuscitation Council (ERC) resuscitation guidelines 2015 recommend extracorporeal membrane oxygenation (ECMO) as treatment option for therapy refractory out-of-hospital cardiac arrests (OHCA). ECMO used under cardiopulmonary resuscitation (CPR) is called eCPR (extracorporeal CPR). In the year 2018 eCPR is started to be used in Bern, Switzerland. This study investigates retrospectively the survival and neurologic outcome of patients after OHCA in the region of Bern, Switzerland from 2015-2018. The data will be used as baseline for a prospective evaluation of eCPR cases. The prospective Evaluation of e CPR will last from 2018 - 2022.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2018
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 28, 2018
CompletedFirst Posted
Study publicly available on registry
November 29, 2018
CompletedStudy Start
First participant enrolled
December 15, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2024
CompletedJuly 19, 2023
July 1, 2023
5 years
November 28, 2018
July 18, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Neurologic Outcome after 30 days
CPC 1 - 5 (Cerebral Performance Category Scale)
30 days after OHCA
Eligibility Criteria
All OHCA cases in the region of Bern, Switzerland in the year 2015-2017
You may qualify if:
- All OHCA in the region of Bern, Switzerland in the year 2015-2017
You may not qualify if:
- if patient has previously declined to be included in a study (advance directive)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Department of Anaesthesiology and Pain Medicine
Bern, Switzerland
Related Publications (1)
Ebert F, Abt M, Fehr T, Seidl K, Huber M, Ludwig R, Iten M, Greif R, Nabecker S, Fuchs A. Long-term neurological outcome following out-of-hospital cardiac arrest in Switzerland: a single-centre observational study. Front Med (Lausanne). 2026 Jan 2;12:1716369. doi: 10.3389/fmed.2025.1716369. eCollection 2025.
PMID: 41551516DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY CHAIR
Robert Greif, Prof., M.D.
University Hospital Bern, Bern, Switzerland
- PRINCIPAL INVESTIGATOR
Sabine Nabecker, M.D.
University Hospital Bern, Bern, Switzerland
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 28, 2018
First Posted
November 29, 2018
Study Start
December 15, 2018
Primary Completion
December 30, 2023
Study Completion
June 1, 2024
Last Updated
July 19, 2023
Record last verified: 2023-07
Data Sharing
- IPD Sharing
- Will not share