Personality Disorders and Substance Use Disorders in a Sexual Context in the Man Having Sex With Other Men Population

NCT03753737 | Completed

• 2 other identifiers: 69HCL18_05092018-A02168-47
• Study Type: observational
• Target: 94
• Locations: 1 country
• Sites: 1

Brief Summary

Chemsex refers to the use of psychoactive drugs in a sexual context, mainly cathinones, GHB/GBL, methamphetamine, cocaine and ketamine. This can cause infectious or psychiatric complications, addictions, and often goes with high risk sexual behaviours. Recent studies have highlighted the relationship between personality disorders, substance use disorders and risky sexual behaviours. It is important to understand the factors associated with chemsex in order to offer adapted prevention and care plans. The study hypothesis is that personality disorders, evaluated with the PDQ-4+ questionnaire, are more frequent among man having sex with other men with a substance use disorder linked to chemsex than among man having sex with other men who have never practised chemsex.

Conditions

Substance Use Disorders

Outcome Measures

Primary Outcomes (1)

• Personality disorders

  Positive score for 1 or more DSM-V personality disorders(PD) using French version of the PDQ4+,Personality Diagnostic Questionnaire-Version4,comprising: * Combined score of overall personality disturbance (ranges0 to 93);higher values reflect a more important personality disturbance * Borderline PD:Score Ranges(SR) 0 to 9,positive(+) if ≥ 5 * Narcissistic PD:SR 0 to 9,+ if ≥5 * Histrionic PD:SR 0 to 8,+ if ≥5 * Antisocial PD:SR 0 to 8,+ if ≥4 and criteria 99 positive * Avoidant PD:SR 0 to 7,+ if ≥4 * Dependent PD:SR 0 to 8,+ if ≥5 * Obsessive-Compulsive PD:SR 0 to 8,+ if ≥4 * Paranoid PD:SR 0 to 7,+ if ≥4 * Schizoid PD:SR 0 to 7,+ if ≥4 * Schizotypal PD:SR 0 to 9,+ if ≥5 * Questionnaire must be interpreted with caution if 1 of the 2 "Suspect Questionnaire" items is +, or if at least 2 of the 4 "Too Good" items are + * Negativistic and depressive PD are evaluated with the PDQ4+ but are not part of the outcome measures in the study

  1 day

Study Arms (2)

Chemsex

Men who have Sex with Men (MSM) attending an addiction care center for past or present mild, moderate or severe substance-related disorder(s) according to DSM-V criteria, occurring in a sexual context and concerning cathinones, GHB/GBL, methamphetamine, cocaine and/or ketamine.

Other: Questionnaires and semi-structured interview

Control

Men who have Sex with Men (MSM) consulting for a PrEP (HIV Pre-Exposure Prophylaxis) prescription who have never used cathinones, GHB/GBL, methamphetamine, cocaine or ketamine before or during sex.

Other: Questionnaires and semi-structured interview

Interventions

Questionnaires and semi-structured interview OTHER

* Questionnaires : PDQ-4+ (personality disorders), HAD (Anxiety and Depression), AUDIT-c (Alcohol consumption), CTQ-SF (Childhood Trauma Questionnaire). * Semi-structured interview : Evaluation of socio-demographic characteristics, psychiatric and addiction comorbidities, sexually transmitted infections, sexual practices, sexual dysfunction, hypersexual disorder.

Chemsex; Control

Eligibility Criteria

• Age: 18 Years+
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Men who have Sex with Men (MSM) with past or present substance-related disorder related to chemsex, and sexually active MSM who have never experienced chemsex.

You may qualify if:

• Age over 18
• Men who have Sex with Men
• No opposition to participate to the study
• Chemsex group: to attend an addiction care center for past or present mild, moderate or severe substance-related disorder(s) according to DSM-V criteria, occurring in a sexual context and concerning cathinones, GHB/GBL, methamphetamine, cocaine and/or ketamine.
• Control group: to consult for a PrEP prescription and never have used cathinones, GHB/GBL, methamphetamine, cocaine or ketamine before or during sex.

You may not qualify if:

• Deprivation of liberty
• Guardianship
• Chemsex group: simple experience of chemsex without substance use disorder

Sponsors & Collaborators

• Hospices Civils de Lyon: lead

Study Sites (1)

CSAPA - Service Hépato-gastroentérologie

Lyon, 69004, France

Location

MeSH Terms

Conditions

Substance-Related Disorders

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Chemically-Induced Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 22, 2018
• First Posted: November 27, 2018
• Study Start: November 22, 2018
• Primary Completion: April 29, 2019
• Study Completion: April 29, 2019
• Last Updated: May 22, 2019

Record last verified: 2019-05

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)