NCT03749473

Brief Summary

To use a randomized controlled trial to test the effectiveness of four goal-setting strategies within a gamification intervention to increase physical activity among adults at elevated risk for ASCVD.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
500

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Jan 2019

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 14, 2018

Completed
7 days until next milestone

First Posted

Study publicly available on registry

November 21, 2018

Completed
2 months until next milestone

Study Start

First participant enrolled

January 14, 2019

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2020

Completed
Last Updated

June 4, 2020

Status Verified

June 1, 2020

Enrollment Period

1.4 years

First QC Date

November 14, 2018

Last Update Submit

June 2, 2020

Conditions

Keywords

Physical ActivityGoal-SettingGamification

Outcome Measures

Primary Outcomes (1)

  • Change in mean daily steps from baseline to maintenance period.

    The primary outcome is change in mean daily steps from baseline to weeks 9-16 (maintenance period).

    Baseline to weeks 9-16

Secondary Outcomes (1)

  • Change in mean daily steps from baseline to follow-up period.

    Baseline to the weeks 17 to 24

Other Outcomes (2)

  • Change in minutes of MVPA from baseline to maintenance and follow-up periods.

    Baseline to weeks 9-16 and weeks 17-24

  • Change in minutes of sleep from baseline to maintenance and follow-up periods.

    Baseline to weeks 9-16 and weeks 17-24

Study Arms (5)

Control

ACTIVE COMPARATOR

Participants receive a daily message with their step count on the prior day to serve as an active control for 24 weeks (daily performance feedback). No other interventions during the 24-week study

Behavioral: Daily performance feedback

Choice + Immediate

EXPERIMENTAL

Participants choose a step goal between 1000-3000 steps greater than their baseline (choice). They are asked to reach their full step goal upon intervention start (immediate). They will be in a gamification intervention for the first 16 weeks and then receive only daily feedback during the 8-week follow-up

Behavioral: Choice + ImmediateBehavioral: Daily performance feedbackBehavioral: Gamification

Choice + Gradual

EXPERIMENTAL

Participants are asked to choose a step goal between 1000-3000 steps greater than their baseline (choice). They will be asked to increase their step goal by even increments of 12.5% each week for the 8 weeks of the ramp-up period (gradual). After the 8-week ramp-up period, they will be asked to maintain the step goal for the study. They may change their goal within the range at anytime. They will be in a gamification intervention for the first 16 weeks and then receive only daily feedback during the 8-week follow-up

Behavioral: Choice + GradualBehavioral: Daily performance feedbackBehavioral: Gamification

Assigned + Immediate

EXPERIMENTAL

Participants in this arm will be assigned a step goal 2000 steps greater than their baseline (assigned). They will be asked to reach their full step goal as soon as the intervention begins (immediate). They will be in a gamification intervention for the first 16 weeks and then receive only daily feedback during the 8-week follow-up

Behavioral: Assigned + ImmediateBehavioral: Daily performance feedbackBehavioral: Gamification

Assigned + Gradual

EXPERIMENTAL

Participants in this arm will be assigned a step goal 2000 steps greater than their baseline (assigned). They will be asked to achieve their step goal of 2000 steps incrementally over the 8 weeks of the ramp-up period (gradual). After the first 8 weeks, they will be asked to maintain their full step goal of 2000 for the the study. They will be in a gamification intervention for the first 16 weeks and then receive only daily feedback during the 8-week follow-up

Behavioral: Assigned + GradualBehavioral: Daily performance feedbackBehavioral: Gamification

Interventions

Participants in the choice + immediate goal arm will choose a step goal and must attempt to achieve this new step goal immediately at the start of the study.

Choice + Immediate

Participants in the choice + gradual goal arm will choose a step goal and will gradually work towards the chosen step goal over the first 8-weeks of the study.

Choice + Gradual

Participants in the assigned + immediate goal arm will be assigned a step goal and must attempt to achieve this new step goal immediately at the start of the study.

Assigned + Immediate

Participants in the assigned + gradual goal arm will be assigned a step goal and will gradually work towards the chosen step goal over the first 8-weeks of the study.

Assigned + Gradual

Participants will receive daily performance feedback on their daily step count.

Assigned + GradualAssigned + ImmediateChoice + GradualChoice + ImmediateControl
GamificationBEHAVIORAL

All participants in the intervention arms will be entered into a gamification platform that has points and levels designed to incorporate insights from behavioral economics.

Assigned + GradualAssigned + ImmediateChoice + GradualChoice + Immediate

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years or older;
  • ability to read and provide informed consent to participate in the study;
  • diagnosis of clinical ASCVD or a 10-year ASCVD risk score ≥ 7.5% calculated according to the 2013 ACC/AHA guidelines;
  • Smartphone or tablet compatible with application for the wearable activity tracking device.

You may not qualify if:

  • Conditions that would make participation infeasible such as inability to provide informed consent, illiteracy or inability to speak, read, and write English;
  • conditions that would make participation unsafe such as pregnancy or being told by a physician not to exercise;
  • already enrolled in another study targeting physical activity;
  • any other medical conditions or reasons he or she is unable to participate in a physical activity study for 24 weeks;
  • baseline step count of 10,000 steps or greater.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Perelman Center for Advanced Medicine

Philadelphia, Pennsylvania, 19104, United States

Location

Related Publications (1)

  • Patel MS, Bachireddy C, Small DS, Harrison JD, Harrington TO, Oon AL, Rareshide CAL, Snider CK, Volpp KG. Effect of Goal-Setting Approaches Within a Gamification Intervention to Increase Physical Activity Among Economically Disadvantaged Adults at Elevated Risk for Major Adverse Cardiovascular Events: The ENGAGE Randomized Clinical Trial. JAMA Cardiol. 2021 Dec 1;6(12):1387-1396. doi: 10.1001/jamacardio.2021.3176.

MeSH Terms

Conditions

AtherosclerosisMotor Activity

Condition Hierarchy (Ancestors)

ArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesBehavior

Study Officials

  • Mitesh S Patel, MD, MBA, MS

    University of Pennsylvania

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
HEALTH SERVICES RESEARCH
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

November 14, 2018

First Posted

November 21, 2018

Study Start

January 14, 2019

Primary Completion

June 1, 2020

Study Completion

June 1, 2020

Last Updated

June 4, 2020

Record last verified: 2020-06

Data Sharing

IPD Sharing
Will not share

Individual participant data will not be made available

Locations