NCT03747666

Brief Summary

Evaluating the biting force after management of parasymphyseal fracture in patients with two-line mandibular fractures.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Nov 2019

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 12, 2018

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 20, 2018

Completed
12 months until next milestone

Study Start

First participant enrolled

November 1, 2019

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2019

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2020

Completed
Last Updated

February 19, 2019

Status Verified

February 1, 2019

Enrollment Period

Same day

First QC Date

November 12, 2018

Last Update Submit

February 18, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Biting force

    Biting force will be measured using occlusal biting force meter (Higher biting force record is better)

    6 months

Secondary Outcomes (7)

  • Stability of fractured segments

    6 weeks

  • Pain intensity

    10 days

  • Occlusion

    6 months

  • Infection

    6 months

  • Hardware failure

    6 months

  • +2 more secondary outcomes

Study Arms (2)

Locking miniplate

EXPERIMENTAL

The fractured segments in the parasymphyseal region will be fixed using 2.0 single locking miniplates and the fractured segments of the angle will be fixed conventionally using 2.0 single non-locking miniplate placed on the external oblique ridge.

Procedure: 2.0 single locking miniplates

Non-locking miniplates

EXPERIMENTAL

The fractured segments in the parasymphyseal region will be fixed using 2.0 two non-locking miniplates and the fractured segments of the angle will be fixed conventionally using 2.0 single non-locking miniplate placed on the external oblique ridge.

Procedure: 2.0 single locking miniplates

Interventions

The fractured segments in the parasymphyseal region will be fixed using 2.0 single locking miniplates placed on the inferior border of the mandible.

Locking miniplateNon-locking miniplates

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Contra-lateral unfavorable non-comminuted simple or compound mandibular fracture in the parasymphyseal and angle regions.
  • Fractures amenable to treatment using intra oral approach.

You may not qualify if:

  • Medically compromised patients who are unfit for the procedure under general anesthesia.
  • Patients with comminuted fractures.
  • Patients with history of occlusion disturbances or skeletal malocclusion.
  • Patients with insufficient dentition to reproduce occlusion.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Mandibular Fractures

Condition Hierarchy (Ancestors)

Jaw FracturesMaxillofacial InjuriesFacial InjuriesCraniocerebral TraumaTrauma, Nervous SystemNervous System DiseasesSkull FracturesFractures, BoneWounds and Injuries

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

November 12, 2018

First Posted

November 20, 2018

Study Start

November 1, 2019

Primary Completion

November 1, 2019

Study Completion

November 1, 2020

Last Updated

February 19, 2019

Record last verified: 2019-02