Reducing Disparities in Medication Adherence in SLE
2 other identifiers
interventional
135
1 country
1
Brief Summary
This is a pilot study to assess the feasibility of using Surescripts refill data during the clinical encounter to improve medication adherence in patients with systemic lupus erythematosus
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Oct 2019
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 6, 2018
CompletedFirst Posted
Study publicly available on registry
November 13, 2018
CompletedStudy Start
First participant enrolled
October 2, 2019
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 7, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
June 7, 2020
CompletedResults Posted
Study results publicly available
July 27, 2021
CompletedJune 17, 2025
June 1, 2025
8 months
November 6, 2018
May 27, 2021
June 13, 2025
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Feasibility as Measured by Number of Participants With EMR (Electronic Medical Record) Documentation of Adherence
Feasibility as measured by documentation of adherence assessment made by provider.
12 weeks
Acceptability as Measured by Provider Survey
Acceptability as measured by provider survey, score range 1-5, with a higher score indicating that the intervention was more acceptable.
12 weeks
Secondary Outcomes (2)
Medication Adherence as Determined by Self Report
12 weeks
Percentage of Adherent Participants as Determined by Medication Possession Ratio (MPR)
Baseline, 12 weeks
Study Arms (1)
Intervention arm
EXPERIMENTALLupus clinic providers will use Surescripts refill information to assess adherence level and address adherence barriers. We will assess the feasibility and acceptability of the intervention.
Interventions
Lupus clinic providers will be prompted to assess adherence level using Surescripts refill information and address any adherence barriers that arise during the clinical encounter.
Eligibility Criteria
You may qualify if:
- \- All followup patients seen at the Duke Lupus clinic
You may not qualify if:
- Patients not seen at the Duke Lupus Clinic
- New patients seen for the first time at the Duke Lupus Clinic
- Patients who are not prescribed any lupus medications
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Duke University
Durham, North Carolina, 27710, United States
Related Publications (1)
Sun K, Eudy AM, Rogers JL, Criscione-Schreiber LG, Sadun RE, Doss J, Maheswaranathan M, Barr AC, Eder L, Corneli AL, Bosworth HB, Clowse MEB. Pilot Intervention to Improve Medication Adherence Among Patients With Systemic Lupus Erythematosus Using Pharmacy Refill Data. Arthritis Care Res (Hoboken). 2023 Mar;75(3):550-558. doi: 10.1002/acr.24806. Epub 2022 Nov 11.
PMID: 34739191DERIVED
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Results Point of Contact
- Title
- Kai Sun, M.D.
- Organization
- Duke University
Study Officials
- PRINCIPAL INVESTIGATOR
Kai Sun
Duke University
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- HEALTH SERVICES RESEARCH
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 6, 2018
First Posted
November 13, 2018
Study Start
October 2, 2019
Primary Completion
June 7, 2020
Study Completion
June 7, 2020
Last Updated
June 17, 2025
Results First Posted
July 27, 2021
Record last verified: 2025-06