Attempted Suicide Short Intervention Program: a Randomized Controlled Trial

NCT03732300 | Completed

• 1 other identifier: EASI
• Study Type: interventional
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

"Attempted Suicide Short Intervention Program" (ASSIP) is a brief psychotherapy intervention after suicide attempts in psychiatric patients. The study aims to analyse the efficacy in a controlled trial by comparing number of patients with suicide attempts in a control group with treatment as usual and an intervention group with treatment as usual and ASSIP intervention. Further, the study aims at indentifying electrophysiological, sociodempgraphical or smartphone-derived parameters for prediction of further suicide attempts.

Conditions

Suicidality; Suicide, Attempted

Outcome Measures

Primary Outcomes (1)

• suicide/attempted suicide

  number of patients with attempted suicide or suicide

  12 months

Secondary Outcomes (4)

• Number of toal suicide attempts

  3,6,12 months

• Hospitalization rates

  12 months

• EEG-vigilance

  baseline

• ECG Heart Rate Variability

  baseline

Study Arms (2)

ASSIP + TAU goup

EXPERIMENTAL

ASSIP psychotherapy intervention + treatment as usual (TAU)

Other: ASSIP

TAU

NO INTERVENTION

Treatment as usual

Interventions

ASSIP OTHER

Three PSychotherapy Sessions plus after 3/6/9/12 months individualized letters

Also known as: Attempted Suicide Short Intervention Program

ASSIP + TAU goup

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Informed Consent as documented by signature (Appendix Informed Consent Form)
• Age 18 or older
• Treatment in and outpatient clinic of the University Hospital of Psychiatry Zurich, a daycare clinic or on a ward of the University Hospital of Psychiatry Zurich
• Able and willing to comply with all study requirements, especially being able to participate and understand psychotherapy sessions

You may not qualify if:

• Acute psychosis with delusion and/or hallucination
• Dementia
• Insufficient ability to communicate in German language
• Chronic self-harming behaviour without a direct intention of suicide (Wolfersdorf \& Etzersdorfer, 2011)
• Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant,
• Current electroconvulsive therapy (do to interference between cognitive side effects and psychotherapeutic intervention)
• Participation in another study with investigational drug within the 30 days preceding and during the present study,
• Previous enrolment into the current study,
• Enrolment of the investigator, his/her family members, employees and other dependent persons,

Sponsors & Collaborators

• University of Zurich: lead

Study Sites (1)

Department for Psychiatry, University Zurich

Zurich, Switzerland

Location

Related Publications (2)

• Gysin-Maillart A, Schwab S, Soravia L, Megert M, Michel K. A Novel Brief Therapy for Patients Who Attempt Suicide: A 24-months Follow-Up Randomized Controlled Study of the Attempted Suicide Short Intervention Program (ASSIP). PLoS Med. 2016 Mar 1;13(3):e1001968. doi: 10.1371/journal.pmed.1001968. eCollection 2016 Mar.

  PMID: 26930055 BACKGROUND

• Witt KG, Hetrick SE, Rajaram G, Hazell P, Taylor Salisbury TL, Townsend E, Hawton K. Psychosocial interventions for self-harm in adults. Cochrane Database Syst Rev. 2021 Apr 22;4(4):CD013668. doi: 10.1002/14651858.CD013668.pub2.

  PMID: 33884617 DERIVED

MeSH Terms

Conditions

Suicidal Ideation; Suicide, Attempted

Condition Hierarchy (Ancestors)

Suicide; Self-Injurious Behavior; Behavioral Symptoms; Behavior

Study Officials

• Sebastian Olbrich

  Department for Psychiatry, Psychotherapy and Psychosomatics, University Zurich

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Deputy Head of Center for Social Psychiatry

Model Details: Monocenter, open-label, randomized parallel two study arms (ASSIP vs control)

Study Record Dates

• First Submitted: November 1, 2018
• First Posted: November 6, 2018
• Study Start: December 1, 2018
• Primary Completion: February 28, 2023
• Study Completion: November 1, 2023
• Last Updated: May 8, 2024

Record last verified: 2024-05

Locations

CH (1)