Study About Treatment After a Suicide Attempt

NCT03894462 | Completed DMC

• 1 other identifier: 3353
• Study Type: interventional
• Target: 443
• Locations: 1 country
• Sites: 3

Brief Summary

Effective, brief, low-cost interventions for individuals who attempt suicide are needed to save lives and achieve the goals of the National Strategy for Suicide Prevention. In response to a National Institute for Mental Health (NIMH) Notice of Interest, this time-sensitive proposal leverages an existing federal investment in Zero Suicide to test the effectiveness of a highly promising new treatment for recent suicide attempt survivors and learn how it works. If hypotheses are supported, the study will provide evidence of a brief, practical, and cost-effective therapy that reduces suicide reattempts in a real-world health setting.

Conditions

Suicide, Attempted

Keywords

Zero Suicide; Effectiveness; Brief Treatment; Interpersonal Theory; Cost-Effectiveness

Outcome Measures

Primary Outcomes (1)

• Time to Suicide Attempt

  Time from randomization to first suicide re-attempt

  Up to 18 months

Study Arms (2)

Zero Suicide Usual Care

ACTIVE COMPARATOR

In Onondaga County, New York State (NYS) aims to implement a countywide "Zero Suicide Safety Net" of providers who share enhanced protocols for clinical care, staff training, and data collection (improved coding of suicidal behavior). Participating behavioral health systems have agreed to common protocols for clinical care, training, and data collection. Participating providers receive robust training in suicide prevention best practices. Because of the wide participation of mental health facilities in the NYS Office of Mental Health (OMH) Zero Suicide project, most subjects who engage in outpatient treatment will receive that treatment in facilities that are adopting NYS Zero Suicide protocols. Those who do not engage in care will nonetheless experience enhanced transition and follow-up contact from the services from which they are discharged.

Behavioral: Zero Suicide Usual Care

Zero Suicide Usual Care + ASSIP

EXPERIMENTAL

Patients in this treatment arm will receive ASSIP brief therapy in addition to being able to access any usual care as recommended by their provider. ASSIP is a manualized, three-session intervention, delivered either in-person or via telehealth: In Session 1, the therapist guides the patient in telling the story of their attempt. The session is video recorded. In Session 2, the therapist and patient sit side-by-side to view selections of the video, working together to understand the feelings and events that preceded the attempt. The patient is assigned a homework task. In Session 3, the therapist and patient create a summary of the suicide attempt and what led up to it, along with creating a personal safety plan.

Behavioral: Attempted Suicide Short Intervention Program

Interventions

Attempted Suicide Short Intervention Program BEHAVIORAL

ASSIP is a manualized, three-session intervention, delivered either in-person or via telehealth: In Session 1, the therapist guides the patient in telling the story of their attempt. The session is video recorded. In Session 2, the therapist and patient sit side-by-side to view selections of the video, working together to understand the feelings and events that preceded the attempt. The patient is assigned a homework task. In Session 3, the therapist and patient create a summary of the suicide attempt and what led up to it, along with creating a personal safety plan.

Zero Suicide Usual Care + ASSIP

Zero Suicide Usual Care BEHAVIORAL

Participants will have access to outpatient treatment in facilities that are adopting NYS Zero Suicide protocols. Those who do not engage in care will nonetheless experience enhanced transition and follow-up contact from the services from which they are discharged.

Zero Suicide Usual Care

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• years or older.
• Suicide attempt within the past 60 days defined by intent to die using a standard item.
• Ability and willingness to provide information and permission to contact at least one person in the case of a need to contact them to promote subject safety or inability to reach the subject for follow-up.

You may not qualify if:

• Acute psychiatric instability (e.g., psychotic symptoms).
• Inability to communicate in English (ASSIP is only provided by the clinic in English).
• Residing outside of NYS (during the period eligible for ASSIP)

Sponsors & Collaborators

• University of Rochester: lead
• Northwestern University: collaborator
• Hutchings Psychiatric Center: collaborator
• University of Arkansas: collaborator
• State University of New York - Upstate Medical University: collaborator

Study Sites (3)

University of Rochester Medical Center

Rochester, New York, 14604, United States

Location

St. Joseph's Health Hospital

Syracuse, New York, 13203, United States

Location

Upstate University Hospital

Syracuse, New York, 13210, United States

Location

Related Publications (3)

• Gysin-Maillart A, Schwab S, Soravia L, Megert M, Michel K. A Novel Brief Therapy for Patients Who Attempt Suicide: A 24-months Follow-Up Randomized Controlled Study of the Attempted Suicide Short Intervention Program (ASSIP). PLoS Med. 2016 Mar 1;13(3):e1001968. doi: 10.1371/journal.pmed.1001968. eCollection 2016 Mar.

  PMID: 26930055 BACKGROUND

• Pisani A, Connor K, Van Orden K, Jordan N, Landes S, Curran G, McDermott M, Ertefaie A, Kelberman C, Ramanathan S, Carruthers J, Mossgraber K, Goldston D. Effectiveness of a targeted brief intervention for recent suicide attempt survivors: a randomised controlled trial protocol. BMJ Open. 2023 Mar 3;13(3):e070105. doi: 10.1136/bmjopen-2022-070105.

  PMID: 36868590 DERIVED

• Witt KG, Hetrick SE, Rajaram G, Hazell P, Taylor Salisbury TL, Townsend E, Hawton K. Psychosocial interventions for self-harm in adults. Cochrane Database Syst Rev. 2021 Apr 22;4(4):CD013668. doi: 10.1002/14651858.CD013668.pub2.

  PMID: 33884617 DERIVED

MeSH Terms

Conditions

Suicide, Attempted

Condition Hierarchy (Ancestors)

Suicide; Self-Injurious Behavior; Behavioral Symptoms; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: CARE PROVIDER
• Masking Details: We do not inform providers giving usual care whether their patients are receiving ASSIP. However, providers may find out through ordinary course of usual care being provided.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Randomized controlled trial

Study Record Dates

• First Submitted: February 12, 2019
• First Posted: March 28, 2019
• Study Start: April 1, 2021
• Primary Completion: April 1, 2025
• Study Completion: April 1, 2025
• Last Updated: April 6, 2025

Record last verified: 2024-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (3)