NCT03214783

Brief Summary

The purpose of this study is to explore the facial characteristics associated with the increased risk of coronary artery diseases. The secondary purpose is to evaluate the diagnostic efficacy of appearance factors for coronary artery diseases.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,300

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

July 8, 2017

Completed
2 days until next milestone

Study Start

First participant enrolled

July 10, 2017

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 12, 2017

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2018

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 31, 2018

Completed
Last Updated

November 6, 2018

Status Verified

November 1, 2018

Enrollment Period

1.3 years

First QC Date

July 8, 2017

Last Update Submit

November 5, 2018

Conditions

Coronary Artery Disease

Keywords

artificial intelligencefacial recognitionfacial characteristic

Outcome Measures

Primary Outcomes (1)

  • The association between facial factors and increased risk of coronary artery diseases

    at the end of enrollment (6 months)

Study Arms (2)

Coronary artery disease (CAD) group

Patients enrolled with at least one coronary lesion stenosis ≥50% according to coronary computer tomography or coronary angiography will be assigned to CAD group.

Other: Facial characteristics

No CAD group

Patients enrolled without coronary lesion stenosis ≥50% according to coronary computer tomography or coronary angiography will be assigned to CAD group.

Other: Facial characteristics

Interventions

Facial characteristicsOTHER

The exposures are facial characteristics which differ significantly in exposure rates between coronary artery disease (CAD) group and no CAD group.

Coronary artery disease (CAD) groupNo CAD group

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who undergo coronary computer tomography or coronary angiography from both resident patients and outpatient.

You may qualify if:

  • Undergoing coronary computer tomography or coronary angiography
  • Written informed consent

You may not qualify if:

  • Prior percutaneous coronary intervention (PCI)
  • Prior coronary artery bypass graft (CABG)
  • Without blood biochemistry outcome
  • With artificially facial alteration (i.e. cosmetic surgery, facial trauma or make-up)
  • Other situations which make patients fail to be photographed

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Fuwai Hospital Chinese Academay of Medical Science and National Center for Cardiovascular Diseases

Beijing, Beijing Municipality, 100037, China

Location

MeSH Terms

Conditions

Coronary Artery Disease

Condition Hierarchy (Ancestors)

Coronary DiseaseMyocardial IschemiaHeart DiseasesCardiovascular DiseasesArteriosclerosisArterial Occlusive DiseasesVascular Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 8, 2017

First Posted

July 12, 2017

Study Start

July 10, 2017

Primary Completion

October 31, 2018

Study Completion

October 31, 2018

Last Updated

November 6, 2018

Record last verified: 2018-11

Locations

CN(1)