NCT03730532

Brief Summary

Supporting patients in exerting choice over their treatment is a central aspect of modern healthcare. In Improving Access to Psychological Therapies (IAPT) services, then patients treated at step 2 are only and always offered cognitive-behaviourally informed guided self-help (GSH), when they are deemed suitable for treatment at step 2 of IAPT services (termed CBT-GSH). Step 2 interventions are guided self-help (GSH) delivered by Psychological Wellbeing Practitioners (PWPs). Recently, a new type of GSH has been developed and found to be feasible and effective in IAPT services - this is called cognitive-analytic guided self-help (CAT-GSH). This research aims to test the efficacy of CAT-GSH by comparing outcomes over time achieved in both types of GSH and interviewing participants about their experience of the GSH. The methodology to support patient choice is a patient preference trial. In this method, then patients that meet inclusion criteria for the trial are offered and choose between either CAT-GSH and CBT-GSH. Those patients that are unconcerned with the type of treatment are randomised to either CAT-GSH or CBT-GSH. The primary outcome measure is the Beck Anxiety Inventory. No changes to the standard practice of the PWPs will occur during the trial, the trial will be situated in a standard IAPT service and be a therefore conducted in a routine practice setting.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
134

participants targeted

Target at P50-P75 for not_applicable anxiety

Timeline
Completed

Started Jan 2019

Typical duration for not_applicable anxiety

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 16, 2018

Completed
20 days until next milestone

First Posted

Study publicly available on registry

November 5, 2018

Completed
3 months until next milestone

Study Start

First participant enrolled

January 29, 2019

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2020

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2020

Completed
Last Updated

February 5, 2019

Status Verified

February 1, 2019

Enrollment Period

1.4 years

First QC Date

October 16, 2018

Last Update Submit

February 1, 2019

Conditions

Keywords

Guided self helpCognitive Analytic TherapyCognitive Behavioral Therapy

Outcome Measures

Primary Outcomes (1)

  • Beck Anxiety Inventory

    measuring change in anxiety at four time points

    Measured at screening, at 6 weeks, 12 weeks and 24 weeks

Secondary Outcomes (2)

  • Generalised Anxiety Disorder - 7

    Measured at screening, weekly for 6 weeks, then at 12 week and 24 week follow-up

  • patient health questionnaire - 9

    Measured at screening, weekly for 6 weeks, then at 12 week and 24 week follow-up

Study Arms (4)

Randomised CBT

EXPERIMENTAL

Cognitive Behavioural Therapy Guided Self Help

Other: Cognitive Behavioural Therapy Guided Self Help

Randomised CAT

EXPERIMENTAL

Cognitive Analytic Therapy Guided Self Help

Other: Cognitive Analytic Therapy Guided Self Help

Preference CAT

EXPERIMENTAL

Cognitive Analytic Therapy Guided Self Help

Other: Cognitive Analytic Therapy Guided Self Help

Preference CBT

EXPERIMENTAL

Cognitive Behavioural Therapy Guided Self Help

Other: Cognitive Behavioural Therapy Guided Self Help

Interventions

6-week manualised Cognitive Behavioural Therapy Guided Self Help

Preference CBTRandomised CBT

6-week manualised Cognitive Analytic Therapy Guided Self Help

Preference CATRandomised CAT

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • patients have self-referred or been referred by their GP or other health or social care professional for a step 2 intervention for treatment of a common mental health problem,
  • patients meet criteria for an anxiety disorder on MINI screening interview assessment and also met caseness on the BAI (as defined by a score of \>10 on the BAI at assessment).
  • Patients want to engage in GSH to address the anxiety disorder
  • patients are motivated to engage in treatment and can attend six sessions of face-to-face GSH.

You may not qualify if:

  • engaging in any another IAPT step 2 interventions.
  • Do not meet criteria for an anxiety disorder as defined by the MINI and the BAI score.
  • Meet criteria for depression and a comorbid anxiety disorder, as identified by the BAI and MINI, where the depression is more severe and is the patient's main concern.
  • Have a severe/chronic mental health problem and are already involved in psychiatric or secondary care mental health services.
  • Have substance misuse issues that would interfere with engagement with the GSH.
  • Have a diagnosed learning disability that precludes engagement in GSH.
  • Have a diagnosis of social phobia or PTSD

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Oldham Healthy Minds IAPT

Oldham, Lancashire, OL11RU, United Kingdom

RECRUITING

Related Publications (1)

  • Kellett S, Bee C, Smithies J, Aadahl V, Simmonds-Buckley M, Power N, Dugen-Williams C, Fallon N, Delgadillo J. Cognitive-behavioural versus cognitive-analytic guided self-help for mild-to-moderate anxiety: a pragmatic, randomised patient preference trial. Br J Psychiatry. 2023 Sep;223(3):438-445. doi: 10.1192/bjp.2023.78.

MeSH Terms

Conditions

Anxiety Disorders

Condition Hierarchy (Ancestors)

Mental Disorders

Study Officials

  • Steve Kellett

    University of Sheffield

    STUDY DIRECTOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: Patient Preference Trial
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Trainee Clinical Psychologist

Study Record Dates

First Submitted

October 16, 2018

First Posted

November 5, 2018

Study Start

January 29, 2019

Primary Completion

July 1, 2020

Study Completion

September 1, 2020

Last Updated

February 5, 2019

Record last verified: 2019-02

Data Sharing

IPD Sharing
Will not share

Locations