The Reliability, Validity, and Responsiveness of the Timed 360° Turn Test in Patients With Multiple Sclerosis

NCT03718026 | Completed

• 1 other identifier: 438
• Study Type: observational
• Target: 95
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of the study is to investigate reliability, validity, and responsiveness of the timed 360° turn test in patients with Multiple Sclerosis.

Conditions

Multiple Sclerosis, Relapsing-Remitting

Keywords

The timed 360° turn test; Multiple sclerosis; reliability; validity

Outcome Measures

Primary Outcomes (1)

• The timed 360° turn test

  The timed 360° turn test evaluates turning ability. Higher durations indicate worse turning performance.

  1 minute

Secondary Outcomes (5)

• Berg Balance Scale

  10 minutes

• Timed Up and Go test

  1 minute

• Functional Reach Test

  1 minute

• Four Square Step Test

  1 minute

• One Leg Stance Test

  3 minutes

Study Arms (2)

Patients with Multiple Sclerosis

* The timed 360° turn test * Berg Balance Scale * Timed Up and Go test * Functional Reach Test * One-leg stance test * Four square step test

Other: The timed 360° turn test

Healthy Controls

-The timed 360° turn test

Other: The timed 360° turn test

Interventions

The timed 360° turn test OTHER

* The timed 360° turn test: Each participant turns around in place in a standing position for both sides. * Berg Balance Scale: It has 14 items, each of which is scored from 0 (i.e, severely impaired balance) to 4 (i.e., no balance impairment). * Timed Up and Go test: It requires individual to stand up from an armed chair, walk 3m, turn around, walk back to the armed chair, and sit down again. * Functional Reach Test: It measures the maximum distance an individual is able to reach forward beyond arm's length in the standing position when maintaining a fixed base of support. * One-leg stance test: Individuals were asked to stand on either their left or right leg. * Four square step test: It requires an individual to step over obstacles in various directions including forward, backward, and sideways.

Also known as: Berg Balance Scale, Timed Up and Go test, Functional Reach Test, One-leg stance test, Four square step test

Healthy Controls; Patients with Multiple Sclerosis

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with Multiple Sclerosis who apply to Gazi University, Department of Physiotherapy and Rehabilitation will be invited to this study.

You may qualify if:

• at least 18 years,
• neurologist-diagnosed Multiple Sclerosis,
• Expanded Disability Status Scale (EDSS) score \< 7,
• able to walk 20 m with or without aids,
• no MS exacerbation within the last 2 months,
• use of stable medication in the last 2 months.

You may not qualify if:

• other neurologic disorder,
• Pregnancy,
• orhopedic problems affecting gait and stance,
• visual, auditory, orientational problems that could affect study results,
• Cardiovascular, pulmonary, and humoral disease.

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Fatih Söke

Ankara, 06560, Turkey (Türkiye)

Location

Related Publications (4)

• Adusumilli G, Lancia S, Levasseur VA, Amblee V, Orchard M, Wagner JM, Naismith RT. Turning is an important marker of balance confidence and walking limitation in persons with multiple sclerosis. PLoS One. 2018 Jun 7;13(6):e0198178. doi: 10.1371/journal.pone.0198178. eCollection 2018.

  PMID: 29879144 BACKGROUND

• Spain RI, St George RJ, Salarian A, Mancini M, Wagner JM, Horak FB, Bourdette D. Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed. Gait Posture. 2012 Apr;35(4):573-8. doi: 10.1016/j.gaitpost.2011.11.026. Epub 2012 Jan 25.

  PMID: 22277368 BACKGROUND

• Gunn H, Creanor S, Haas B, Marsden J, Freeman J. Frequency, characteristics, and consequences of falls in multiple sclerosis: findings from a cohort study. Arch Phys Med Rehabil. 2014 Mar;95(3):538-45. doi: 10.1016/j.apmr.2013.08.244. Epub 2013 Sep 18.

  PMID: 24055784 BACKGROUND

• Cameron MH, Asano M, Bourdette D, Finlayson ML. People with multiple sclerosis use many fall prevention strategies but still fall frequently. Arch Phys Med Rehabil. 2013 Aug;94(8):1562-6. doi: 10.1016/j.apmr.2013.01.021. Epub 2013 Feb 4.

  PMID: 23391522 BACKGROUND

MeSH Terms

Conditions

Multiple Sclerosis, Relapsing-Remitting; Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• Fatih Söke

  Gazi University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Research Assistant

Study Record Dates

• First Submitted: October 22, 2018
• First Posted: October 24, 2018
• Study Start: October 24, 2018
• Primary Completion: November 16, 2018
• Study Completion: November 19, 2018
• Last Updated: November 21, 2018

Record last verified: 2018-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)