Gum Acacia and Blood Glucose

NCT03716479 | Completed

• 1 other identifier: STUDY00004203
• Study Type: interventional
• Target: 48
• Locations: 1 country
• Sites: 1

Brief Summary

This study will provide needed insight on the satiety and blood glucose and l effects of the soluble fiber gum acacia at 20g and 40g doses.

Conditions

Diet Modification

Outcome Measures

Primary Outcomes (2)

• Blood glucose levels

  Blood will be taken via finger stick

  0, 30, 60, 120, 180, and 240 minutes after breakfast; Area under the curve (AUC) will be calculated for each treatment

• Appetite Sensation

  Subjective visual analog scale (VAS) will be utilized to assess hunger, fullness and desire to eat

  15, 30, 45, 60, 90, 120, 180 and 240 minutes after breakfast; Area under the curve (AUC) will be calculated for each treatment

Study Arms (3)

0 fiber

EXPERIMENTAL

0 grams fiber added to orange juice

Other: Placebo/Control

low fiber

EXPERIMENTAL

20 grams of acacia gum added to orange juice

Other: Low Fiber

high fiber

EXPERIMENTAL

40 grams of acacia gum added to orange juice

Other: High Fiber

Interventions

Low Fiber OTHER

20 g of acacia gum will be added to orange juice

low fiber

High Fiber OTHER

40 g of acacia gum will be added to orange juice

high fiber

Placebo/Control OTHER

No acacia gum will be added to orange juice.

0 fiber

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may not qualify if:

• distaste for bagels and cream cheese, orange juice or cheese pizza;
• current smoker;
• restrained eating habits;
• recent weight change;
• any history of disease or significant past medical history;
• are vegetarian;
• do not normally eat breakfast or lunch;
• pregnant or lactating;
• irregular menstrual cycles.

Sponsors & Collaborators

• University of Minnesota: lead

Study Sites (1)

Department of Food Science and Nutrition

Saint Paul, Minnesota, 55108, United States

Location

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: fiber will be mixed into orange juice
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Model Details: subjects will consume 0, and 2 doses of acacia gum

Study Record Dates

• First Submitted: August 29, 2018
• First Posted: October 23, 2018
• Study Start: October 9, 2018
• Primary Completion: August 31, 2019
• Study Completion: September 1, 2019
• Last Updated: October 4, 2019

Record last verified: 2019-10

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)