Effects of Pilates Exercise Program in Patients With Schizophrenia

NCT03714698 | Completed

• 1 other identifier: 2015-84-21/10
• Study Type: interventional
• Target: 25
• Locations: 1 country
• Sites: 1

Brief Summary

Schizophrenia is one of the most frequent psychiatric disorders with a prevalence of 0.5-1.0 % all over the world. It remains one of the major reasons for disability although medical and psychosocial interventions. People suffering from schizophrenia may also have many complex health troubles such as cardiovascular disease, metabolic disease, diabetes mellitus, and pulmonary problems. Researchers have been debating the utility of exercise over depression, anxiety, and obsessive-compulsive symptoms last decades. Studies indicate that physical activity improves mood, self-esteem, energy, motivation, concentration, cognitive skills, quality of life, and social interactions. Particularly in the last decade studies have been carried out showing that various exercise approaches and physical activities contribute positively to the physical and mental health of schizophrenic patients. Clinic impacts of these interventions, dominantly including aerobic exercise, strengthening and fitness training, also varied according to the type, duration and intensity of the method used. The knowledge obtained about schizophrenia patients point out that physically and mentally holistic approaches should be required to this complicated disease. Previous trials demonstrated that various physical activity or exercise methods have positive effects in patients with schizophrenia. However, to the best of the our knowledge, literature lacks investigation about benefits of Pilates on several domains, in particular about the potential changes on physical and mental health in patients with schizophrenia. The aim of this study was to investigate the effects of Pilates-based exercise training on the physical and mental health of schizophrenia patients.

Conditions

Schizophrenia

Keywords

Pilates exercise

Outcome Measures

Primary Outcomes (1)

• Change from baseline "6 Minute Walk Test" at 6 week

  The 6MWT is a practical simple test that requires a 100-ft hallway but no exercise equipment or advanced training for technicians. Walking is an activity performed daily by all but the most severely impaired patients. This test measures the distance that a patient can quickly walk on a flat, hard surface in a period of 6 minutes (the 6MWD). It evaluates the global and integrated responses of all the systems involved during exercise, including the pulmonary and cardiovascular systems, systemic circulation, peripheral circulation, blood, neuromuscular units, and muscle metabolism. The self-paced 6MWT assesses the submaximal level of functional capacity. Most patients do not achieve maximal exercise capacity during the 6MWT; instead, they choose their own intensity of exercise and are allowed to stop and rest during the test.

  at the baseline and after six weeks

Secondary Outcomes (4)

• Change from baseline Calgary Depression Scale for Schizophrenia at 6 week

  at the baseline and after six weeks

• Change from baseline The Scale for the Assessment of Negative Symptoms at 6 week

  at the baseline and after six weeks

• Change from baseline The Scale for the Assessment of Positive Symptoms (SAPS) at 6 week

  at the baseline and after six weeks

• Change from baseline The Brief Psychiatric Rating Scale at 6 week

  at the baseline and after six weeks

Study Arms (2)

Pilates Exercise Group

ACTIVE COMPARATOR

Pilates exercise group participated in supervised Pilates-based group training twice per week for six weeks

Other: Pilates exercise group

Control Group

PLACEBO COMPARATOR

the control group participated in a routine non-specific activity program twice a week in Community Mental Health Center during study

Other: Control Group

Interventions

Pilates exercise group OTHER

Pilates exercise group participated in supervised Pilates-based group training twice per week for six weeks

Also known as: non-specific, activity, program

Pilates Exercise Group

Control Group OTHER

The control group participated in a routine non-specific activity program twice a week in Community Mental Health Center during study

Control Group

Eligibility Criteria

• Age: 35 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may not qualify if:

• Patients with a severe physical disability or a physical condition that makes their participation impossible or potentially harmful (such as serious musculoskeletal or neurological disabilities) were excluded from the study. Additionally, patients who did not attend at least 10 of the 12 training sessions in the study group were excluded from the study.

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Zonguldak Bülent Ecevit University

Zonguldak, 67600, Turkey (Türkiye)

Location

Related Publications (4)

• Beebe LH, Tian L, Morris N, Goodwin A, Allen SS, Kuldau J. Effects of exercise on mental and physical health parameters of persons with schizophrenia. Issues Ment Health Nurs. 2005 Jul;26(6):661-76. doi: 10.1080/01612840590959551.

  PMID: 16020076 BACKGROUND

• Rimes RR, de Souza Moura AM, Lamego MK, de Sa Filho AS, Manochio J, Paes F, Carta MG, Mura G, Wegner M, Budde H, Ferreira Rocha NB, Rocha J, Tavares JM, Arias-Carrion O, Nardi AE, Yuan TF, Machado S. Effects of Exercise on Physical and Mental Health, and Cognitive and Brain Functions in Schizophrenia: Clinical and Experimental Evidence. CNS Neurol Disord Drug Targets. 2015;14(10):1244-54. doi: 10.2174/1871527315666151111130659.

  PMID: 26556069 BACKGROUND

• Oertel-Knochel V, Mehler P, Thiel C, Steinbrecher K, Malchow B, Tesky V, Ademmer K, Prvulovic D, Banzer W, Zopf Y, Schmitt A, Hansel F. Effects of aerobic exercise on cognitive performance and individual psychopathology in depressive and schizophrenia patients. Eur Arch Psychiatry Clin Neurosci. 2014 Oct;264(7):589-604. doi: 10.1007/s00406-014-0485-9. Epub 2014 Feb 2.

  PMID: 24487666 BACKGROUND

• Firth J, Cotter J, Elliott R, French P, Yung AR. A systematic review and meta-analysis of exercise interventions in schizophrenia patients. Psychol Med. 2015 May;45(7):1343-61. doi: 10.1017/S0033291714003110. Epub 2015 Feb 4.

  PMID: 25650668 BACKGROUND

MeSH Terms

Conditions

Schizophrenia

Interventions

Exercise; Control Groups

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena; Epidemiologic Research Design; Epidemiologic Methods; Investigative Techniques; Research Design; Methods

Study Officials

• Eda AKBAŞ, Assist.Prof.

  Zonguldak Bulent Ecevit University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: Both groups received the similar medication (atypical antipsychotic drugs) during the study. Patients in the control group participated in a non-specific activity programme including conventional exercise training, hobby and social interaction activities routinely twice a week, at the community mental health center during six weeks. The PEG participated in a supervised Pilates exercise program twice per week for six weeks (totally 12 sessions).
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor, PhD., PT

Model Details: Pilates exercise group participated in supervised Pilates-based group training twice per week for six weeks, while the control group participated in a routine non-specific activity program twice a week in Community Mental Health Center during study

Study Record Dates

• First Submitted: October 19, 2018
• First Posted: October 22, 2018
• Study Start: October 12, 2016
• Primary Completion: July 15, 2018
• Study Completion: July 15, 2018
• Last Updated: October 24, 2018

Record last verified: 2018-10

Locations

TU (1)