NCT03708081

Brief Summary

Postoperative pain is a frequent complication associated with root canal treatment. The apical extrusion of irrigant and debris, including bacteria and necrotic tissue, may lead to postoperative pain, periapical inflammation, and flare-ups. The instrumentation technique and the file design may affect the amount of debris extrusion. The aim of this study was to evaluate the influence of instrumentation techniques on the incidence and intensity of postoperative pain after single-visit root canal treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2017

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 10, 2018

Completed
25 days until next milestone

Study Completion

Last participant's last visit for all outcomes

October 5, 2018

Completed
6 days until next milestone

First Submitted

Initial submission to the registry

October 11, 2018

Completed
6 days until next milestone

First Posted

Study publicly available on registry

October 17, 2018

Completed
Last Updated

December 20, 2018

Status Verified

December 1, 2018

Enrollment Period

1.3 years

First QC Date

October 11, 2018

Last Update Submit

December 19, 2018

Conditions

Outcome Measures

Primary Outcomes (1)

  • Post operative pain

    Postoperative pain which occurs after root canal instrumentation and measured with a commonly used scale named 'four-point pain intensity scale' for pain intensity. Patients were instructed postoperatively to express their pain according to the staed scale ranging between no pain and severe pain. The scale consists of 4 scores ranging between 1-4. The pain categories were as follows; 1. no pain; 2. mild pain (slight discomfort, no need for treatment); 3. moderate pain (pain relieved by medication); 4. severe pain (pain and/or swelling not relieved by simple analgesic medication and unscheduled visit required). For patients having no pain score 1, for patients having slight pain in case of no medication score 2 , and score 3 in case of any requirement of medication due to moderate pain, and score 4 for patients having severe pain with the requirement of an unscheduled visit were accepted. The higher values represent more pain intensity.

    2 days

Study Arms (2)

Group 1

Root canal treatments will be completed by ProTaper Next instruments with rotational motion

Procedure: ProTaper Next

Group 2

Root canal treatments will be completed TF Adaptive instruments with adaptive motion.

Procedure: TF Adaptive

Interventions

ProTaper NextPROCEDURE

Root canal instrument

Group 1
TF AdaptivePROCEDURE

Root canal instrument

Group 2

Eligibility Criteria

Sexall
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

patients referred to dental clinic for endodontic treatment

You may qualify if:

  • having root canal treatment indication
  • single root canal

You may not qualify if:

  • previously treated tooth

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Bülent Ecevit University, Faculty of Dentistry

Zonguldak, Turkey (Türkiye)

Location

MeSH Terms

Conditions

PulpitisPeriapical PeriodontitisDental Pulp Necrosis

Condition Hierarchy (Ancestors)

Dental Pulp DiseasesTooth DiseasesStomatognathic DiseasesPeriapical DiseasesJaw DiseasesPeriodontal DiseasesMouth DiseasesPeriodontitisNecrosisPathologic ProcessesPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
2 Days
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate professor

Study Record Dates

First Submitted

October 11, 2018

First Posted

October 17, 2018

Study Start

June 1, 2017

Primary Completion

September 10, 2018

Study Completion

October 5, 2018

Last Updated

December 20, 2018

Record last verified: 2018-12

Locations