NCT03301259

Brief Summary

The aim of this study is to evaluate the post treatment pain after instrumentation of root canals with a single file reciprocating (Wave-One Ni Ti file, DENTSPLY Maillefer) or rotary(One Shape, Micro Mega, France) file system in patient with asymptomatic necrotic molars This trial will help to clinically evaluate the use of reciprocating motion in endodontic treatment in necrotic teeth without periapical lesion therefore reduce the post-obtuation pain

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
42

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Jan 2018

Shorter than P25 for not_applicable

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 24, 2017

Completed
10 days until next milestone

First Posted

Study publicly available on registry

October 4, 2017

Completed
3 months until next milestone

Study Start

First participant enrolled

January 15, 2018

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 15, 2018

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 15, 2018

Completed
Last Updated

December 5, 2017

Status Verified

December 1, 2017

Enrollment Period

4 months

First QC Date

September 24, 2017

Last Update Submit

December 3, 2017

Conditions

Keywords

Necrotic pulpwave-oneone-shapeperiapical lesion

Outcome Measures

Primary Outcomes (1)

  • Post operative pain

    Post operative pain after mechanical preparation with wave one and one shape using VAS scale from 0 to 10 Post-operative pain is defined as any degree of pain that occurs after initiation of root canal treatment, while flare up is defined as the development or continuation of pain and/or swelling after endodontic treatment. The will be asked to record the level of pain at 6 hours, 24 hours, 48 hours and 7days after obturation. The patient will be trained that 0 is no pain, 10 is the worst pain that interfere with his daily routine, and he will be asked to estimate the pain as follows: 0 No pain. From 1-3 mild pain. From 4-5 moderate pain. From 7-10 severe pain

    changes after 6 hours , 24 hours , 48 hours , 7 days The patient will be trained that 0 is no pain, 10 is the worst pain that interfere with his daily routine, and he will be asked to estimate the pain from 0 to 10

Study Arms (2)

wave -one reciprocating system

EXPERIMENTAL

The reciprocating single file systems WaveOne (Maillefer, Ballaigues, Switzerland) provide more flexibility of the M-wire Ni-Ti alloy, greater resistance to cyclic fatigue and better handling of narrow and curved canals than the traditional Ni-Ti instruments Root canal preparation will be done with theWaveOne System with strict adherence to the manufacturer's instructions. After coronal preflaring with File ISO 21 taper 8% instrument with 2.5% sodium hypochlorite as the irrigant, working length was determined and a glide path will created. The Red file R 25 taper 8% will be used for preparing the mesial canal; and the Black ISO 40 taper 8% file will be used for preparing the distal canals where there is only a single canal.

Other: One-shape rotationary system

OneShape

EXPERIMENTAL

OneShape (MICRO-MEGA) rotary nickel-titanium use roation movement and available in two sizes N°30 - .06 rotary files. , N°25 - .06

Other: One-shape rotationary system

Interventions

OneShape (MICRO-MEGA) rotary nickel-titanium use roation movement and available in two sizes N°30 - .06 rotary files. , N°25 - .06

OneShapewave -one reciprocating system

Eligibility Criteria

Age25 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Medically free patients
  • Patient's age between 25-50 years.
  • Mandibular molars diagnosed clinically as necrotic with normal apical tissues.
  • Positive patient's acceptance for participation in the study.
  • Both genders are included.
  • Patients able to sign informed consent.
  • Normal periodontal tissues.
  • Normal periapical tissues on the radiograph

You may not qualify if:

  • Patients with complicating systemic disease.
  • Having severe pain and/or acute apical abscesses.
  • Under the age of 25 years.
  • Patients using antibiotics or analgesic 12 hours before the procedures.
  • Having multiple teeth that required treatment.
  • With non-restorable and/or periodontally compromised teeth.
  • Retreatment cases
  • Presence of sinus tract
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Dental Pulp Necrosis

Condition Hierarchy (Ancestors)

Dental Pulp DiseasesTooth DiseasesStomatognathic DiseasesNecrosisPathologic ProcessesPathological Conditions, Signs and Symptoms

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
master candidate at endodontic department faculty of oral and dental medicine CU

Study Record Dates

First Submitted

September 24, 2017

First Posted

October 4, 2017

Study Start

January 15, 2018

Primary Completion

May 15, 2018

Study Completion

August 15, 2018

Last Updated

December 5, 2017

Record last verified: 2017-12