NCT03703999

Brief Summary

Aim of the study is to evaluate efficacy of freestyle Libre system (flash glucose monitoring) in real life in term of Glycated Haemoglobin reduction and acceptance of the system evaluated through validated questionnaires after 3 and 6 months of device's use.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2018

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2018

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 20, 2018

Completed
22 days until next milestone

First Posted

Study publicly available on registry

October 12, 2018

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2019

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2019

Completed
Last Updated

March 27, 2020

Status Verified

March 1, 2020

Enrollment Period

10 months

First QC Date

September 20, 2018

Last Update Submit

March 26, 2020

Conditions

Keywords

flash glucose monitoringHbA1c

Outcome Measures

Primary Outcomes (1)

  • HbA1c

    changes in HbA1c values

    after 3 and 6 months

Secondary Outcomes (5)

  • changes in hypoglycemia fear

    after 3 and 6 months

  • changes in therapy satisfaction

    after 3 and 6 months

  • hypoglycemic episodes

    after 3 and 6 months

  • weight

    after 3 and 6 months

  • insulin use

    after 3 and 6 months

Study Arms (1)

type 1 diabetic patients freestyle Libre

group of type 1 diabetic patients that will be selected to use Freestyle libre on the basis of clinicians decisions and reimbursement criteria

Device: Type 1 diabetic patients freestyle libre

Interventions

patients selected to use freestyle libre

type 1 diabetic patients freestyle Libre

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

type 1 diabetic patients selected by clinicians to start Freestyle Libre use

You may qualify if:

  • Male and female participants of at least 18 years of age
  • Diagnosis of type 1 diabetes mellitus (diagnosed according to World Health Organization criteria) for at least 1 year
  • Availability to wear Freestyle Libre sensor
  • Signature of informed consent

You may not qualify if:

  • Pregnancy, breastfeeding, intention to undergo pregnancy
  • Known allergies to skin patches or disinfectants used during the study.
  • Skin lesions, irritation, redness, edema in sites where sensors can be applied, as this might interfere with sensor's placement
  • Use of drugs that may interfere with glucose metabolism (such as steroids) unless they are chronic therapies whose dosage has remained stable over the past 3 months and is expected to remain stable during the study period.
  • Severe medical or psychological conditions, which, in the opinion of the medical team, may compromise patients' safety while using freestyle LIbre sensor
  • Patients enrolled in other clinical trials.
  • patients that usually wear other continuous glucose monitoring system

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Padova

Padua, Italy

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune DiseasesImmune System Diseases

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
MD, PhD

Study Record Dates

First Submitted

September 20, 2018

First Posted

October 12, 2018

Study Start

June 1, 2018

Primary Completion

April 1, 2019

Study Completion

September 1, 2019

Last Updated

March 27, 2020

Record last verified: 2020-03

Data Sharing

IPD Sharing
Will not share

Locations