NCT03694574

Brief Summary

Our aim is to compare state anger and state emotion regulation strategies in healthy individuals with high trait schizotypy and to look at differences of induced anger, negative emotions, decrease of positive emotions and aggressive behaviour after anger induction. Our further aim is to compare conditions where an instruction to suppress or reappraise emotions is given with a control condition with no instruction.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
131

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2016

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2016

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 31, 2017

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2017

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

October 1, 2018

Completed
2 days until next milestone

First Posted

Study publicly available on registry

October 3, 2018

Completed
Last Updated

October 9, 2018

Status Verified

October 1, 2018

Enrollment Period

1.2 years

First QC Date

October 1, 2018

Last Update Submit

October 5, 2018

Conditions

Outcome Measures

Primary Outcomes (4)

  • state anger

    measured by the German version of State-Trait Anger Expression Inventory (Schwenkmetzger, Hodapp, \& Spielberger, 1992)

    3 minutes

  • state negative emotions

    measured by the German Version of Positive and Negative Affect Schedule (Krohne, Egloff, Kohlmann, \& Tausch, 1996)

    3 minutes

  • state positive emotions

    measured by the German Version of Positive and Negative Affect Schedule (Krohne, Egloff, Kohlmann, \& Tausch, 1996)

    3 minutes

  • aggressive behavior

    measured by the amount of chili measured by the Hot Sauce Paradigm (Lieberman, Solomon, Greenberg, \& McGregor, 1999)

    3 minutes

Study Arms (2)

Low schizotypy

OTHER

Schizotypy score \< 14 measured by the German Version of Schizotypal Personality Questionnaire (Klein, Andresen, \& Jahn, 1997)

Behavioral: instruction to suppressBehavioral: instruction to reappraiseBehavioral: control

High schizotypy

OTHER

Schizotypy score ≥ 14 measured by the German Version of Schizotypal Personality Questionnaire (Klein, Andresen, \& Jahn, 1997)

Behavioral: instruction to suppressBehavioral: instruction to reappraiseBehavioral: control

Interventions

"It might happen that in some situations in which you try to do something and you fail or things don't come up as you want, you could become angry, mad or irritated and feel some level of distress and discomfort. Next, try not to think of the situation that makes you angry, mad or irritated. Please try as much as you cannot to think about the situation, don't think about how you feel or what had happened, and try to suppress your emotions and not to feel them. It's very important to try as much as you cannot to think about the situation that makes you angry, mad or irritated." (Szasz, Szentagothai, \& Hoffmann, 2011)

High schizotypyLow schizotypy

"It might happen that in some situations in which you try to do something and you fail or things don't come up as you want, you could become angry, mad or irritated and feel some level of distress and discomfort. Next, please try to tell yourself that or would be preferable that the others are nice and/or fair to you, but if they are not, it does not mean that you or they are worthless human beings. It would be preferable that the others be nice and/or fair to you but if they are not, remember that it is only (very) bad), not catastrophic (the worst thing that could happen to you). It would be preferable that others are nice and/or fair to you, but if they are not, you can tolerate it, and go on enjoying life, even if it's more difficult at the beginning." (Szasz et al., 2011)

High schizotypyLow schizotypy
controlBEHAVIORAL

No instruction

High schizotypyLow schizotypy

Eligibility Criteria

Age18 Years - 58 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • age between 18 and 58 years,
  • good command of German language

You may not qualify if:

  • present or past psychiatric or neurological illness,
  • ongoing treatment with psychiatric drugs,
  • constant consume of heroin or hallucinogenic drugs,
  • alcohol dependence,
  • cannabis consume two weeks before testing.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (5)

  • Klein, C., Andresen, B., & Jahn, T. (1997). Erfassung der schizotypen Persönlichkeit nach DSM-III-R: Psychometrische Eigenschaften einer autorisierten deutschsprachigen Übersetzung des

    BACKGROUND
  • Krohne, H. W., Egloff, B., Kohlmann, C. W., & Tausch, A. (1996). Untersuchung mit einer deutschen Form der Positive and Negative Affect Schedule (PANAS). Diagnostica, 42, 139-156.

    BACKGROUND
  • Lieberman, J. D., Solomon, S., Greenberg, J. & McGregor, H. A. (1999). A hot new way to measure aggression: hot sauce allocation, Aggressive Behavior, 25, 331-348

    BACKGROUND
  • Schwenkmetzger, P., Hodapp, V., & Spielberger, C. D. (1992). Das State-Trait-Ärgerausdrucks-Inventar (STAXI). Bern: Huber.

    BACKGROUND
  • Szasz PL, Szentagotai A, Hofmann SG. The effect of emotion regulation strategies on anger. Behav Res Ther. 2011 Feb;49(2):114-9. doi: 10.1016/j.brat.2010.11.011. Epub 2010 Dec 9.

    PMID: 21185551BACKGROUND

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
academic staff

Study Record Dates

First Submitted

October 1, 2018

First Posted

October 3, 2018

Study Start

March 1, 2016

Primary Completion

May 31, 2017

Study Completion

September 30, 2017

Last Updated

October 9, 2018

Record last verified: 2018-10