Opportunities and Limits to Deprescribing in Nursing Homes:Quality Circle Deprescribing Module
OLD-NH-QC-DeMo
1 other identifier
interventional
56
1 country
1
Brief Summary
Older people residing in nursing homes (NH) are frequently polymedicated and often prescribed potentially inappropriate medications. Deprescribing has been proposed as a way to reduce the number of drugs they receive and their exposure to harmful treatments. The objectives of this study are 1) To evaluate the effect of a deprescribing-specific interdisciplinary quality circle module on the use of potentially inappropriate medication in nursing-home residents. 2) To determine the effective strategies to reach and implement deprescribing consensus resulting of said quality circle module.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Sep 2017
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 25, 2017
CompletedFirst Submitted
Initial submission to the registry
September 26, 2018
CompletedFirst Posted
Study publicly available on registry
September 28, 2018
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 1, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
July 1, 2020
CompletedResults Posted
Study results publicly available
April 21, 2021
CompletedApril 21, 2021
March 1, 2021
2.8 years
September 26, 2018
November 10, 2020
March 24, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (2)
Percentage of Potentially Inappropriate Galenic Units
The primary outcome is the percentage, at follow-up, of potentially inappropriate galenic units at follow-up, relative to the total number of galenic units used in the nursing home.
12 months
Number of Potentially Inappropriate Defined Daily Doses (DDDs) Per Average Resident and Per Day
Sum of Defined Daily Doses identified as potentially inappropriate (PIM, see protocol for assessement method), divided by the total number of days spent in the NH
12 months
Secondary Outcomes (6)
Number of Potentially Inappropriate DDD to Avoid
12 months
Number of Potentially Inappropriate DDD to Reevaluate
12 months
Number of Hospital Days
12 months
Mortality Rate
12 months
Number of Falls Per Average Resident and Per Year
12 months
- +1 more secondary outcomes
Study Arms (2)
Intervention
EXPERIMENTALNursing Homes allocated to the Intervention arm will enact the Quality Circle Deprescribing Module and create a local deprescribing consensus and implementation strategy.
Control
NO INTERVENTIONNursing Homes allocated to the Control arm will not enact the intervention.
Interventions
The Quality Circle Deprescribing Module consist of a discussion bringing together nurses, physicians and responsible pharmacist to create a local deprescribing consensus for frequently used drug classes, as well as implementation strategies for the consensus..
Eligibility Criteria
You may qualify if:
- Nursing homes taking part in the study must have
- a geriatric of psycho-geriatric mission;
- been part of their cantonal pharmaceutical assistance program for at least a year.
You may not qualify if:
- None
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Anne Niquillelead
Study Sites (1)
Centre de Pharamacie Communautaire
Lausanne, Canton of Vaud, 1011, Switzerland
Related Publications (4)
Mena S, Moullin JC, Schneider M, Niquille A. Implementation of interprofessional quality circles on deprescribing in Swiss nursing homes: an observational study. BMC Geriatr. 2023 Oct 3;23(1):620. doi: 10.1186/s12877-023-04335-w.
PMID: 37789286DERIVEDCateau D, Ballabeni P, Niquille A. Effects of an interprofessional deprescribing intervention in Swiss nursing homes: the Individual Deprescribing Intervention (IDeI) randomised controlled trial. BMC Geriatr. 2021 Nov 19;21(1):655. doi: 10.1186/s12877-021-02465-7.
PMID: 34798826DERIVEDCateau D, Ballabeni P, Niquille A. Effects of an interprofessional Quality Circle-Deprescribing Module (QC-DeMo) in Swiss nursing homes: a randomised controlled trial. BMC Geriatr. 2021 May 1;21(1):289. doi: 10.1186/s12877-021-02220-y.
PMID: 33933030DERIVEDCateau D, Ballabeni P, Mena S, Bugnon O, Niquille A. Deprescribing in nursing homes: Protocol for nested, randomised controlled hybrid trials of deprescribing interventions. Res Social Adm Pharm. 2021 Apr;17(4):786-794. doi: 10.1016/j.sapharm.2020.05.026. Epub 2020 May 27.
PMID: 32622774DERIVED
Related Links
Results Point of Contact
- Title
- Dr Anne Niquille
- Organization
- Community Pharmacy, Center for Primary Care and Public Health (Unisanté), University of Lausanne, Switzerland
Study Officials
- STUDY DIRECTOR
Olivier Bugnon, Prof
University of Geneva
Publication Agreements
- PI is Sponsor Employee
- Yes
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- OTHER
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Dr
Study Record Dates
First Submitted
September 26, 2018
First Posted
September 28, 2018
Study Start
September 25, 2017
Primary Completion
July 1, 2020
Study Completion
July 1, 2020
Last Updated
April 21, 2021
Results First Posted
April 21, 2021
Record last verified: 2021-03
Data Sharing
- IPD Sharing
- Will not share